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Influence of cigarette filter ventilation on smokers' mouth level exposure to tar and nicotine.
Caraway, John W; Ashley, Madeleine; Bowman, Sheri A; Chen, Peter; Errington, Graham; Prasad, Krishna; Nelson, Paul R; Shepperd, Christopher J; Fearon, Ian M.
Affiliation
  • Caraway JW; RAI Services Company, Winston-Salem, NC, USA.
  • Ashley M; British American Tobacco (Investments) Limited, Research and Development, Regents Park Road, Southampton, SO15 8TL, UK.
  • Bowman SA; RAI Services Company, Winston-Salem, NC, USA.
  • Chen P; RAI Services Company, Winston-Salem, NC, USA.
  • Errington G; British American Tobacco (Investments) Limited, Research and Development, Regents Park Road, Southampton, SO15 8TL, UK.
  • Prasad K; British American Tobacco (Investments) Limited, Research and Development, Regents Park Road, Southampton, SO15 8TL, UK.
  • Nelson PR; RAI Services Company, Winston-Salem, NC, USA.
  • Shepperd CJ; British American Tobacco (Investments) Limited, Research and Development, Regents Park Road, Southampton, SO15 8TL, UK.
  • Fearon IM; British American Tobacco (Investments) Limited, Research and Development, Regents Park Road, Southampton, SO15 8TL, UK. Electronic address: ian_fearon@bat.com.
Regul Toxicol Pharmacol ; 91: 235-239, 2017 Dec.
Article in En | MEDLINE | ID: mdl-29097238
ABSTRACT
Cigarette filter ventilation allows air to be drawn into the filter, diluting the cigarette smoke. Although machine smoking reveals that toxicant yields are reduced, it does not predict human yields. The objective of this study was to investigate the relationship between cigarette filter ventilation and mouth level exposure (MLE) to tar and nicotine in cigarette smokers. We collated and reviewed data from 11 studies across 9 countries, in studies performed between 2005 and 2013 which contained data on MLE from 156 products with filter ventilation between 0% and 87%. MLE among 7534 participants to tar and nicotine was estimated using the part-filter analysis method from spent filter tips. For each of the countries, MLE to tar and nicotine tended to decrease as filter ventilation increased. Across countries, per-cigarette MLE to tar and nicotine decreased as filter ventilation increased from 0% to 87%. Daily MLE to tar and nicotine also decreased across the range of increasing filter ventilation. These data suggest that on average smokers of highly ventilated cigarettes are exposed to lower amounts of nicotine and tar per cigarette and per day than smokers of cigarettes with lower levels of ventilation.
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Smoke / Tars / Tobacco Products / Mouth / Nicotine Limits: Adult / Female / Humans / Male Language: En Journal: Regul Toxicol Pharmacol Year: 2017 Type: Article Affiliation country: United States

Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Smoke / Tars / Tobacco Products / Mouth / Nicotine Limits: Adult / Female / Humans / Male Language: En Journal: Regul Toxicol Pharmacol Year: 2017 Type: Article Affiliation country: United States