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Irreversible Activation and Stabilization of Soluble Guanylate Cyclase by the Protoporphyrin IX Mimetic Cinaciguat.
Kollau, Alexander; Opelt, Marissa; Wölkart, Gerald; Gorren, Antonius C F; Russwurm, Michael; Koesling, Doris; Mayer, Bernd; Schrammel, Astrid.
Affiliation
  • Kollau A; Department of Pharmacology and Toxicology, Karl-Franzens-Universität Graz, Graz, Austria (A.K., M.O., G.W., A.C.F.G., B.M., A.S.); and Department of Pharmacology and Toxicology, Ruhr University Bochum, Bochum, Germany (M.R., D.K.).
  • Opelt M; Department of Pharmacology and Toxicology, Karl-Franzens-Universität Graz, Graz, Austria (A.K., M.O., G.W., A.C.F.G., B.M., A.S.); and Department of Pharmacology and Toxicology, Ruhr University Bochum, Bochum, Germany (M.R., D.K.).
  • Wölkart G; Department of Pharmacology and Toxicology, Karl-Franzens-Universität Graz, Graz, Austria (A.K., M.O., G.W., A.C.F.G., B.M., A.S.); and Department of Pharmacology and Toxicology, Ruhr University Bochum, Bochum, Germany (M.R., D.K.).
  • Gorren ACF; Department of Pharmacology and Toxicology, Karl-Franzens-Universität Graz, Graz, Austria (A.K., M.O., G.W., A.C.F.G., B.M., A.S.); and Department of Pharmacology and Toxicology, Ruhr University Bochum, Bochum, Germany (M.R., D.K.).
  • Russwurm M; Department of Pharmacology and Toxicology, Karl-Franzens-Universität Graz, Graz, Austria (A.K., M.O., G.W., A.C.F.G., B.M., A.S.); and Department of Pharmacology and Toxicology, Ruhr University Bochum, Bochum, Germany (M.R., D.K.).
  • Koesling D; Department of Pharmacology and Toxicology, Karl-Franzens-Universität Graz, Graz, Austria (A.K., M.O., G.W., A.C.F.G., B.M., A.S.); and Department of Pharmacology and Toxicology, Ruhr University Bochum, Bochum, Germany (M.R., D.K.).
  • Mayer B; Department of Pharmacology and Toxicology, Karl-Franzens-Universität Graz, Graz, Austria (A.K., M.O., G.W., A.C.F.G., B.M., A.S.); and Department of Pharmacology and Toxicology, Ruhr University Bochum, Bochum, Germany (M.R., D.K.).
  • Schrammel A; Department of Pharmacology and Toxicology, Karl-Franzens-Universität Graz, Graz, Austria (A.K., M.O., G.W., A.C.F.G., B.M., A.S.); and Department of Pharmacology and Toxicology, Ruhr University Bochum, Bochum, Germany (M.R., D.K.) astrid.schrammel-gorren@uni-graz.at.
Mol Pharmacol ; 93(2): 73-78, 2018 02.
Article in En | MEDLINE | ID: mdl-29138269
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Protoporphyrins / Vasodilation / Benzoates / Molecular Mimicry / Enzyme Inhibitors / Soluble Guanylyl Cyclase Limits: Animals Language: En Journal: Mol Pharmacol Year: 2018 Type: Article
Fulltext
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Protoporphyrins / Vasodilation / Benzoates / Molecular Mimicry / Enzyme Inhibitors / Soluble Guanylyl Cyclase Limits: Animals Language: En Journal: Mol Pharmacol Year: 2018 Type: Article