The role of nonsteroidal anti-inflammatory drugs intramuscular injection in the development and severity of deep soft tissue infection in mice.

Ture, Zeynep; Demiraslan, Hayati; Kontas, Olgun; Alp, Emine; Doganay, Mehmet

Ture, Zeynep; Demiraslan, Hayati; Kontas, Olgun; Alp, Emine; Doganay, Mehmet.

Affiliation

Ture Z; Department of Infectious Diseases and Clinical Microbiology, Faculty of Medicine, Erciyes University, Melikgazi, Kayseri, Turkey.
Demiraslan H; Department of Infectious Diseases and Clinical Microbiology, Faculty of Medicine, Erciyes University, Melikgazi, Kayseri, Turkey.
Kontas O; Department of Pathology, Faculty of Medicine, Erciyes University, Melikgazi, Kayseri, Turkey.
Alp E; Department of Infectious Diseases and Clinical Microbiology, Faculty of Medicine, Erciyes University, Melikgazi, Kayseri, Turkey.
Doganay M; Department of Infectious Diseases and Clinical Microbiology, Faculty of Medicine, Erciyes University, Melikgazi, Kayseri, Turkey.

Fundam Clin Pharmacol ; 32(2): 147-154, 2018 Apr.

Article in En | MEDLINE | ID: mdl-29172254

Subject(s)

Anti-Inflammatory Agents, Non-Steroidal/toxicity; Diclofenac/toxicity; Sepsis/chemically induced; Soft Tissue Infections/chemically induced; Streptococcal Infections/chemically induced; Streptococcus pyogenes/pathogenicity; Abscess/blood; Abscess/chemically induced; Abscess/microbiology; Animals; Anti-Inflammatory Agents, Non-Steroidal/administration & dosage; Bacteremia/blood; Bacteremia/chemically induced; Bacteremia/microbiology; Bacterial Load; Diclofenac/administration & dosage; Disease Models, Animal; Female; Inflammation Mediators/blood; Injections, Intramuscular; Interleukin-6/blood; Mice, Inbred BALB C; Sepsis/blood; Sepsis/microbiology; Sepsis/pathology; Soft Tissue Infections/blood; Soft Tissue Infections/microbiology; Soft Tissue Infections/pathology; Streptococcal Infections/blood; Streptococcal Infections/microbiology; Streptococcal Infections/pathology; Time Factors; Tumor Necrosis Factor-alpha/blood

Key words

Streptococcus pyogenes; TNF-alpha; diclofenac; experimental soft tissue infection; interleukin-6; nonsteroidal anti-inflammatory drugs

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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Streptococcal Infections / Streptococcus pyogenes / Anti-Inflammatory Agents, Non-Steroidal / Diclofenac / Soft Tissue Infections / Sepsis Type of study: Prognostic_studies Limits: Animals Language: En Journal: Fundam Clin Pharmacol Journal subject: FARMACOLOGIA Year: 2018 Type: Article Affiliation country: Turkey

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