Extent of chromosomal mosaicism influences the clinical outcome of in vitro fertilization treatments.

Spinella, Francesca; Fiorentino, Francesco; Biricik, Anil; Bono, Sara; Ruberti, Alessandra; Cotroneo, Ettore; Baldi, Marina; Cursio, Elisabetta; Minasi, Maria Giulia; Greco, Ermanno

Extent of chromosomal mosaicism influences the clinical outcome of in vitro fertilization treatments.

Spinella, Francesca; Fiorentino, Francesco; Biricik, Anil; Bono, Sara; Ruberti, Alessandra; Cotroneo, Ettore; Baldi, Marina; Cursio, Elisabetta; Minasi, Maria Giulia; Greco, Ermanno.

Affiliation

Spinella F; GENOMA Group, Molecular Genetics Laboratories, Rome, Italy.
Fiorentino F; GENOMA Group, Molecular Genetics Laboratories, Rome, Italy. Electronic address: fiorentino@laboratoriogenoma.it.
Biricik A; GENOMA Group, Molecular Genetics Laboratories, Rome, Italy.
Bono S; GENOMA Group, Molecular Genetics Laboratories, Rome, Italy.
Ruberti A; Reproductive Medicine, European Hospital, Rome, Italy.
Cotroneo E; GENOMA Group, Molecular Genetics Laboratories, Rome, Italy.
Baldi M; GENOMA Group, Molecular Genetics Laboratories, Rome, Italy.
Cursio E; Reproductive Medicine, European Hospital, Rome, Italy.
Minasi MG; Reproductive Medicine, European Hospital, Rome, Italy.
Greco E; Reproductive Medicine, European Hospital, Rome, Italy.

Fertil Steril ; 109(1): 77-83, 2018 01.

Article in En | MEDLINE | ID: mdl-29191449

Subject(s)

Aneuploidy; Blastocyst/pathology; Fertilization in Vitro/adverse effects; Infertility/therapy; Mosaicism; Adult; Comparative Genomic Hybridization; Embryo Implantation; Female; Fertility; High-Throughput Nucleotide Sequencing; Humans; Infertility/diagnosis; Infertility/genetics; Infertility/physiopathology; Live Birth; Middle Aged; Predictive Value of Tests; Pregnancy; Pregnancy Rate; Preimplantation Diagnosis/methods; Prospective Studies; Risk Factors; Treatment Outcome

Key words

Preimplantation genetic screening; array-comparative genomic hybridization; embryo aneuploidy; mosaic embryos; next-generation sequencing

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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Blastocyst / Fertilization in Vitro / Infertility / Aneuploidy / Mosaicism Type of study: Diagnostic_studies / Etiology_studies / Observational_studies / Prognostic_studies / Risk_factors_studies Limits: Adult / Female / Humans / Middle aged / Pregnancy Language: En Journal: Fertil Steril Year: 2018 Type: Article Affiliation country: Italy

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