S-Glutathionylation of p47phox sustains superoxide generation in activated neutrophils.

Nagarkoti, Sheela; Dubey, Megha; Awasthi, Deepika; Kumar, Vikas; Chandra, Tulika; Kumar, Sachin; Dikshit, Madhu

Nagarkoti, Sheela; Dubey, Megha; Awasthi, Deepika; Kumar, Vikas; Chandra, Tulika; Kumar, Sachin; Dikshit, Madhu.

Affiliation

Nagarkoti S; Pharmacology Division, CSIR-Central Drug Research Institute, Lucknow, India.
Dubey M; Pharmacology Division, CSIR-Central Drug Research Institute, Lucknow, India.
Awasthi D; Pharmacology Division, CSIR-Central Drug Research Institute, Lucknow, India.
Kumar V; Centre for Cellular and Molecular Platforms, National Centre for Biological Sciences (NCBS-TIFR), Bangalore, India.
Chandra T; King George's Medical University, Lucknow, India.
Kumar S; Pharmacology Division, CSIR-Central Drug Research Institute, Lucknow, India.
Dikshit M; Pharmacology Division, CSIR-Central Drug Research Institute, Lucknow, India. Electronic address: madhu_dikshit@cdri.res.in.

Biochim Biophys Acta Mol Cell Res ; 1865(2): 444-454, 2018 Feb.

Article in En | MEDLINE | ID: mdl-29195919

Subject(s)

NADPH Oxidase 2/metabolism; NADPH Oxidases/metabolism; Neutrophil Activation; Neutrophils/enzymology; Superoxides/metabolism; Humans; Neutrophils/cytology

Key words

N-Formyl-L-methionyl-L-leucyl-L-phenylalanine (fMLP); NADPH oxidase (NOX-2); Neutrophils; Nitric oxide (NO); Oxidative burst; Phorbol 12-myristate 13-acetate (PMA); Phosphorylation; Reactive oxygen species (ROS); S-Glutathionylation; Sustain ROS; p47phox (NCF-1)

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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Superoxides / Neutrophil Activation / NADPH Oxidases / NADPH Oxidase 2 / Neutrophils Type of study: Prognostic_studies Limits: Humans Language: En Journal: Biochim Biophys Acta Mol Cell Res Year: 2018 Type: Article Affiliation country: India

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