Bisphenol A is an exogenous toxin that promotes mitochondrial injury and death in tubular cells.

Bosch-Panadero, Enrique; Mas, Sebastian; Civantos, Esther; Abaigar, Pedro; Camarero, Vanesa; Ruiz-Priego, Alberto; Ortiz, Alberto; Egido, Jesus; González-Parra, Emilio

Bosch-Panadero, Enrique; Mas, Sebastian; Civantos, Esther; Abaigar, Pedro; Camarero, Vanesa; Ruiz-Priego, Alberto; Ortiz, Alberto; Egido, Jesus; González-Parra, Emilio.

Affiliation

Bosch-Panadero E; Renal, Vascular and Diabetes Research Laboratory, Av Reyes Catolicos 2, Madrid, E-28040, Spain.
Mas S; Renal, Vascular and Diabetes Research Laboratory, Av Reyes Catolicos 2, Madrid, E-28040, Spain.
Civantos E; Spanish Biomedical Research Centre in Diabetes and Associated Metabolic Disorders (CIBERDEM), Spain.
Abaigar P; Spanish Biomedical Research Centre in Diabetes and Associated Metabolic Disorders (CIBERDEM), Spain.
Camarero V; Division of Nephrology, Hospital Universitario de Burgos, Burgos, Spain.
Ruiz-Priego A; Division of Nephrology, Hospital Universitario de Burgos, Burgos, Spain.
Ortiz A; Renal, Vascular and Diabetes Research Laboratory, Av Reyes Catolicos 2, Madrid, E-28040, Spain.
Egido J; Renal, Vascular and Diabetes Research Laboratory, Av Reyes Catolicos 2, Madrid, E-28040, Spain.
González-Parra E; Division of Nephrology and Hypertension, IIS-Fundación Jimenez Diaz UAM, Madrid, Spain.

Environ Toxicol ; 33(3): 325-332, 2018 Mar.

Article in En | MEDLINE | ID: mdl-29214717

Subject(s)

Benzhydryl Compounds/toxicity; Environmental Pollutants/toxicity; Kidney Tubules/drug effects; Mitochondria/drug effects; Phenols/toxicity; Antioxidants/metabolism; Apoptosis; Benzhydryl Compounds/metabolism; Cell Death/drug effects; Cell Line; Environmental Pollutants/metabolism; Humans; Kidney Tubules/cytology; Kidney Tubules/metabolism; Mitochondria/metabolism; NF-E2-Related Factor 2/metabolism; Oxidative Stress/drug effects; Oxygen Consumption; Phenols/metabolism

Key words

apoptosis; chronic kidney disease progression; mitochondria; oxidative stress; tubular; uremic toxins

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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Phenols / Benzhydryl Compounds / Environmental Pollutants / Kidney Tubules / Mitochondria Limits: Humans Language: En Journal: Environ Toxicol Journal subject: SAUDE AMBIENTAL / TOXICOLOGIA Year: 2018 Type: Article Affiliation country: Spain

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