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The Anthelmintic Drug Niclosamide and Its Analogues Activate the Parkinson's Disease Associated Protein Kinase PINK1.
Barini, Erica; Miccoli, Ageo; Tinarelli, Federico; Mulholland, Katie; Kadri, Hachemi; Khanim, Farhat; Stojanovski, Laste; Read, Kevin D; Burness, Kerry; Blow, Julian J; Mehellou, Youcef; Muqit, Miratul M K.
Affiliation
  • Barini E; MRC Protein Phosphorylation and Ubiquitylation Unit, University of Dundee, Dow Street, Dundee, DD1 5EH, UK.
  • Miccoli A; School of Pharmacy and Pharmaceutical Sciences, Cardiff University, King Edward VII Avenue, Cardiff, CF10 3NB, UK.
  • Tinarelli F; Centre for Gene Regulation and Expression, University of Dundee, Dow Street, Dundee, DD1 5EH, UK.
  • Mulholland K; MRC Protein Phosphorylation and Ubiquitylation Unit, University of Dundee, Dow Street, Dundee, DD1 5EH, UK.
  • Kadri H; School of Pharmacy and Pharmaceutical Sciences, Cardiff University, King Edward VII Avenue, Cardiff, CF10 3NB, UK.
  • Khanim F; School of Biosciences, University of Birmingham, Edgbaston, Birmingham, B15 2TT, UK.
  • Stojanovski L; Drug Discovery Unit, University of Dundee, Dow Street, Dundee, DD1 5EH, UK.
  • Read KD; Drug Discovery Unit, University of Dundee, Dow Street, Dundee, DD1 5EH, UK.
  • Burness K; MRC PPU Reagents and Services, University of Dundee, Dow Street, Dundee, DD1 5EH, UK.
  • Blow JJ; Centre for Gene Regulation and Expression, University of Dundee, Dow Street, Dundee, DD1 5EH, UK.
  • Mehellou Y; School of Pharmacy and Pharmaceutical Sciences, Cardiff University, King Edward VII Avenue, Cardiff, CF10 3NB, UK.
  • Muqit MMK; MRC Protein Phosphorylation and Ubiquitylation Unit, University of Dundee, Dow Street, Dundee, DD1 5EH, UK.
Chembiochem ; 19(5): 425-429, 2018 03 02.
Article in En | MEDLINE | ID: mdl-29226533
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Protein Kinases / Enzyme Activators / Anthelmintics / Niclosamide Type of study: Risk_factors_studies Limits: Humans Language: En Journal: Chembiochem Journal subject: BIOQUIMICA Year: 2018 Type: Article Affiliation country: United kingdom
Fulltext
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PubMed Links
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Protein Kinases / Enzyme Activators / Anthelmintics / Niclosamide Type of study: Risk_factors_studies Limits: Humans Language: En Journal: Chembiochem Journal subject: BIOQUIMICA Year: 2018 Type: Article Affiliation country: United kingdom