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Hepatocytic expression of human sodium-taurocholate cotransporting polypeptide enables hepatitis B virus infection of macaques.
Burwitz, Benjamin J; Wettengel, Jochen M; Mück-Häusl, Martin A; Ringelhan, Marc; Ko, Chunkyu; Festag, Marvin M; Hammond, Katherine B; Northrup, Mina; Bimber, Benjamin N; Jacob, Thomas; Reed, Jason S; Norris, Reed; Park, Byung; Moller-Tank, Sven; Esser, Knud; Greene, Justin M; Wu, Helen L; Abdulhaqq, Shaheed; Webb, Gabriela; Sutton, William F; Klug, Alex; Swanson, Tonya; Legasse, Alfred W; Vu, Tania Q; Asokan, Aravind; Haigwood, Nancy L; Protzer, Ulrike; Sacha, Jonah B.
Affiliation
  • Burwitz BJ; Vaccine and Gene Therapy Institute, Oregon Health and Science University, Beaverton, OR, 97006, USA. burwitz@ohsu.edu.
  • Wettengel JM; Institute of Virology, Technical University of Munich/Helmholtz Zentrum Munich, Munich, 81675, Germany.
  • Mück-Häusl MA; Institute of Virology, Technical University of Munich/Helmholtz Zentrum Munich, Munich, 81675, Germany.
  • Ringelhan M; Institute of Virology, Technical University of Munich/Helmholtz Zentrum Munich, Munich, 81675, Germany.
  • Ko C; Department of Internal Medicine II, Klinikum rechts der Isar Technical University of Munich, Munich, 81675, Germany.
  • Festag MM; Institute of Virology, Technical University of Munich/Helmholtz Zentrum Munich, Munich, 81675, Germany.
  • Hammond KB; Institute of Virology, Technical University of Munich/Helmholtz Zentrum Munich, Munich, 81675, Germany.
  • Northrup M; Vaccine and Gene Therapy Institute, Oregon Health and Science University, Beaverton, OR, 97006, USA.
  • Bimber BN; Vaccine and Gene Therapy Institute, Oregon Health and Science University, Beaverton, OR, 97006, USA.
  • Jacob T; Oregon National Primate Research Center, Oregon Health and Science University, Beaverton, OR, 97006, USA.
  • Reed JS; Department of Biomedical Engineering, Oregon Health and Science University, Portland, OR, 97239, USA.
  • Norris R; Vaccine and Gene Therapy Institute, Oregon Health and Science University, Beaverton, OR, 97006, USA.
  • Park B; Oregon National Primate Research Center, Oregon Health and Science University, Beaverton, OR, 97006, USA.
  • Moller-Tank S; Public Health and Preventative Medicine, Oregon Health and Science University, Portland, OR, 97239, USA.
  • Esser K; Gene Therapy Center, The University of North Carolina at Chapel Hill, Chapel Hill, NC, 27599, USA.
  • Greene JM; Department of Genetics, The University of North Carolina at Chapel Hill, Chapel Hill, NC, 27514, USA.
  • Wu HL; Department of Biochemistry and Biophysics, The University of North Carolina at Chapel Hill, Chapel Hill, NC, 27599, USA.
  • Abdulhaqq S; Institute of Virology, Technical University of Munich/Helmholtz Zentrum Munich, Munich, 81675, Germany.
  • Webb G; Vaccine and Gene Therapy Institute, Oregon Health and Science University, Beaverton, OR, 97006, USA.
  • Sutton WF; Vaccine and Gene Therapy Institute, Oregon Health and Science University, Beaverton, OR, 97006, USA.
  • Klug A; Vaccine and Gene Therapy Institute, Oregon Health and Science University, Beaverton, OR, 97006, USA.
  • Swanson T; Vaccine and Gene Therapy Institute, Oregon Health and Science University, Beaverton, OR, 97006, USA.
  • Legasse AW; Oregon National Primate Research Center, Oregon Health and Science University, Beaverton, OR, 97006, USA.
  • Vu TQ; Oregon National Primate Research Center, Oregon Health and Science University, Beaverton, OR, 97006, USA.
  • Asokan A; Oregon National Primate Research Center, Oregon Health and Science University, Beaverton, OR, 97006, USA.
  • Haigwood NL; Oregon National Primate Research Center, Oregon Health and Science University, Beaverton, OR, 97006, USA.
  • Protzer U; Department of Biomedical Engineering, Oregon Health and Science University, Portland, OR, 97239, USA.
  • Sacha JB; Center for Spatial Systems Bioscience, Oregon Health and Science University, Portland, OR, 97201, USA.
Nat Commun ; 8(1): 2146, 2017 12 15.
Article in En | MEDLINE | ID: mdl-29247188
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Hepatitis B virus / Hepatocytes / Organic Anion Transporters, Sodium-Dependent / Symporters Limits: Animals / Humans Language: En Journal: Nat Commun Journal subject: BIOLOGIA / CIENCIA Year: 2017 Type: Article Affiliation country: United States
Fulltext
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PubMed Links
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Hepatitis B virus / Hepatocytes / Organic Anion Transporters, Sodium-Dependent / Symporters Limits: Animals / Humans Language: En Journal: Nat Commun Journal subject: BIOLOGIA / CIENCIA Year: 2017 Type: Article Affiliation country: United States