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LSD1 demethylase and the methyl-binding protein PHF20L1 prevent SET7 methyltransferase-dependent proteolysis of the stem-cell protein SOX2.
Zhang, Chunxiao; Hoang, Nam; Leng, Feng; Saxena, Lovely; Lee, Logan; Alejo, Salvador; Qi, Dandan; Khal, Anthony; Sun, Hong; Lu, Fei; Zhang, Hui.
Affiliation
  • Zhang C; From the Department of Chemistry and Biochemistry, University of Nevada, Las Vegas, Nevada 89154 and.
  • Hoang N; the Laboratory of Chemical Genomics, School of Chemical Biology and Biotechnology, Peking University Shenzhen Graduate School, Shenzhen 518055, China.
  • Leng F; From the Department of Chemistry and Biochemistry, University of Nevada, Las Vegas, Nevada 89154 and.
  • Saxena L; From the Department of Chemistry and Biochemistry, University of Nevada, Las Vegas, Nevada 89154 and.
  • Lee L; the Laboratory of Chemical Genomics, School of Chemical Biology and Biotechnology, Peking University Shenzhen Graduate School, Shenzhen 518055, China.
  • Alejo S; From the Department of Chemistry and Biochemistry, University of Nevada, Las Vegas, Nevada 89154 and.
  • Qi D; From the Department of Chemistry and Biochemistry, University of Nevada, Las Vegas, Nevada 89154 and.
  • Khal A; From the Department of Chemistry and Biochemistry, University of Nevada, Las Vegas, Nevada 89154 and.
  • Sun H; From the Department of Chemistry and Biochemistry, University of Nevada, Las Vegas, Nevada 89154 and.
  • Lu F; the Laboratory of Chemical Genomics, School of Chemical Biology and Biotechnology, Peking University Shenzhen Graduate School, Shenzhen 518055, China.
  • Zhang H; From the Department of Chemistry and Biochemistry, University of Nevada, Las Vegas, Nevada 89154 and.
J Biol Chem ; 293(10): 3663-3674, 2018 03 09.
Article in En | MEDLINE | ID: mdl-29358331
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Ovarian Neoplasms / Chromosomal Proteins, Non-Histone / Protein Processing, Post-Translational / Histone-Lysine N-Methyltransferase / SOXB1 Transcription Factors / Histone Demethylases / Neoplasm Proteins Language: En Journal: J Biol Chem Year: 2018 Type: Article
Fulltext
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Ovarian Neoplasms / Chromosomal Proteins, Non-Histone / Protein Processing, Post-Translational / Histone-Lysine N-Methyltransferase / SOXB1 Transcription Factors / Histone Demethylases / Neoplasm Proteins Language: En Journal: J Biol Chem Year: 2018 Type: Article