Racial disparities in the rate of cardiotoxicity of HER2-targeted therapies among women with early breast cancer.

Litvak, Anya; Batukbhai, Bhavina; Russell, Stuart D; Tsai, Hua-Ling; Rosner, Gary L; Jeter, Stacie C; Armstrong, Deborah; Emens, Leisha A; Fetting, John; Wolff, Antonio C; Silhy, Raquel; Stearns, Vered; Connolly, Roisin M

Litvak, Anya; Batukbhai, Bhavina; Russell, Stuart D; Tsai, Hua-Ling; Rosner, Gary L; Jeter, Stacie C; Armstrong, Deborah; Emens, Leisha A; Fetting, John; Wolff, Antonio C; Silhy, Raquel; Stearns, Vered; Connolly, Roisin M.

Affiliation

Litvak A; Department of Medicine, The Johns Hopkins Hospital, Baltimore, Maryland.
Batukbhai B; Department of Medicine, Sinai Hospital, Baltimore, Maryland.
Russell SD; Department of Medicine, The Johns Hopkins Hospital, Baltimore, Maryland.
Tsai HL; Department of Oncology, Sidney Kimmel Comprehensive Cancer Center, Johns Hopkins School of Medicine, Baltimore, Maryland.
Rosner GL; Department of Oncology, Sidney Kimmel Comprehensive Cancer Center, Johns Hopkins School of Medicine, Baltimore, Maryland.
Jeter SC; Department of Oncology, Sidney Kimmel Comprehensive Cancer Center, Johns Hopkins School of Medicine, Baltimore, Maryland.
Armstrong D; Department of Oncology, Sidney Kimmel Comprehensive Cancer Center, Johns Hopkins School of Medicine, Baltimore, Maryland.
Emens LA; Department of Oncology, Sidney Kimmel Comprehensive Cancer Center, Johns Hopkins School of Medicine, Baltimore, Maryland.
Fetting J; Department of Oncology, Sidney Kimmel Comprehensive Cancer Center, Johns Hopkins School of Medicine, Baltimore, Maryland.
Wolff AC; Department of Oncology, Sidney Kimmel Comprehensive Cancer Center, Johns Hopkins School of Medicine, Baltimore, Maryland.
Silhy R; Department of Oncology, Sidney Kimmel Comprehensive Cancer Center, Johns Hopkins School of Medicine, Baltimore, Maryland.
Stearns V; Department of Oncology, Sidney Kimmel Comprehensive Cancer Center, Johns Hopkins School of Medicine, Baltimore, Maryland.
Connolly RM; Department of Oncology, Sidney Kimmel Comprehensive Cancer Center, Johns Hopkins School of Medicine, Baltimore, Maryland.

Cancer ; 124(9): 1904-1911, 2018 05 01.

Article in En | MEDLINE | ID: mdl-29381193

Subject(s)

Antineoplastic Agents, Immunological/adverse effects; Breast Neoplasms/therapy; Cardiotoxicity/ethnology; Health Status Disparities; Receptor, ErbB-2/antagonists & inhibitors; Adult; Aged; Aged, 80 and over; Antibodies, Monoclonal, Humanized/administration & dosage; Antibodies, Monoclonal, Humanized/adverse effects; Antineoplastic Agents, Immunological/administration & dosage; Black People/statistics & numerical data; Breast Neoplasms/immunology; Breast Neoplasms/pathology; Cardiotoxicity/etiology; Cardiotoxicity/prevention & control; Chemotherapy, Adjuvant/adverse effects; Chemotherapy, Adjuvant/methods; Female; Follow-Up Studies; Humans; Mastectomy; Middle Aged; Neoadjuvant Therapy/adverse effects; Neoadjuvant Therapy/methods; Neoplasm Recurrence, Local/prevention & control; Neoplasm Staging; Receptor, ErbB-2/immunology; Receptor, ErbB-2/metabolism; Retrospective Studies; Trastuzumab/administration & dosage; Trastuzumab/adverse effects; White People/statistics & numerical data

Key words

breast cancer; cardiotoxicity; human epidermal growth factor receptor 2 (HER2)-targeted therapy; pertuzumab; race; trastuzumab

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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Breast Neoplasms / Receptor, ErbB-2 / Health Status Disparities / Cardiotoxicity / Antineoplastic Agents, Immunological Type of study: Etiology_studies / Observational_studies / Prognostic_studies / Risk_factors_studies Limits: Adult / Aged / Aged80 / Female / Humans / Middle aged Language: En Journal: Cancer Year: 2018 Type: Article

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