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Arginase-1 expressing microglia in close proximity to motor neurons were increased early in disease progression in canine degenerative myelopathy, a model of amyotrophic lateral sclerosis.
Toedebusch, Christine M; Snyder, John C; Jones, Maria R; Garcia, Virginia B; Johnson, Gayle C; Villalón, Eric L; Coates, Joan R; Garcia, Michael L.
Affiliation
  • Toedebusch CM; Department of Veterinary Medicine and Surgery, University of Missouri, 900 E Campus Dr., Columbia, MO 65211, USA; Division of Biological Sciences, University of Missouri, Bond Life Sciences Center, 1201 E. Rollins St., Columbia, MO 65211, USA.
  • Snyder JC; Department of Statistics, University of Missouri, Columbia, MO 65211, USA.
  • Jones MR; Division of Biological Sciences, University of Missouri, Bond Life Sciences Center, 1201 E. Rollins St., Columbia, MO 65211, USA.
  • Garcia VB; Division of Biological Sciences, University of Missouri, Bond Life Sciences Center, 1201 E. Rollins St., Columbia, MO 65211, USA; Division of Biological Sciences, University of Missouri, LeFevre Hall, 1200 University Avenue, Columbia, MO 65211, USA.
  • Johnson GC; Department of Veterinary Pathobiology, University of Missouri, 800 E. Campus Loop, Columbia, MO 65211, USA.
  • Villalón EL; Division of Biological Sciences, University of Missouri, Bond Life Sciences Center, 1201 E. Rollins St., Columbia, MO 65211, USA.
  • Coates JR; Department of Veterinary Medicine and Surgery, University of Missouri, 900 E Campus Dr., Columbia, MO 65211, USA.
  • Garcia ML; Division of Biological Sciences, University of Missouri, Bond Life Sciences Center, 1201 E. Rollins St., Columbia, MO 65211, USA; Division of Biological Sciences, University of Missouri, LeFevre Hall, 1200 University Avenue, Columbia, MO 65211, USA. Electronic address: garciaml@missouri.edu.
Mol Cell Neurosci ; 88: 148-157, 2018 04.
Article in En | MEDLINE | ID: mdl-29408267
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Arginase / Microglia / Amyotrophic Lateral Sclerosis / Motor Neurons Type of study: Prognostic_studies Limits: Animals Language: En Journal: Mol Cell Neurosci Journal subject: BIOLOGIA MOLECULAR / NEUROLOGIA Year: 2018 Type: Article Affiliation country: United States
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Arginase / Microglia / Amyotrophic Lateral Sclerosis / Motor Neurons Type of study: Prognostic_studies Limits: Animals Language: En Journal: Mol Cell Neurosci Journal subject: BIOLOGIA MOLECULAR / NEUROLOGIA Year: 2018 Type: Article Affiliation country: United States