Rce1: mechanism and inhibition.

Hampton, Shahienaz E; Dore, Timothy M; Schmidt, Walter K

Hampton, Shahienaz E; Dore, Timothy M; Schmidt, Walter K.

Affiliation

Hampton SE; a New York University Abu Dhabi , Abu Dhabi , United Arab Emirates.
Dore TM; a New York University Abu Dhabi , Abu Dhabi , United Arab Emirates.
Schmidt WK; b Department of Chemistry , University of Georgia , Athens , GA , USA.

Crit Rev Biochem Mol Biol ; 53(2): 157-174, 2018 04.

Article in En | MEDLINE | ID: mdl-29424242

Subject(s)

Endopeptidases; Endoplasmic Reticulum; Neoplasm Proteins; Neoplasms; Oxyquinoline; Proteolysis; Animals; Endopeptidases/chemistry; Endopeptidases/genetics; Endopeptidases/metabolism; Endoplasmic Reticulum/chemistry; Endoplasmic Reticulum/enzymology; Endoplasmic Reticulum/genetics; Endoplasmic Reticulum/pathology; Humans; Neoplasm Proteins/antagonists & inhibitors; Neoplasm Proteins/chemistry; Neoplasm Proteins/genetics; Neoplasm Proteins/metabolism; Neoplasms/drug therapy; Neoplasms/enzymology; Neoplasms/genetics; Neoplasms/pathology; Oxyquinoline/analogs & derivatives; Oxyquinoline/chemistry; Oxyquinoline/therapeutic use; Protease Inhibitors; Structure-Activity Relationship; Substrate Specificity; ras Proteins/chemistry; ras Proteins/genetics; ras Proteins/metabolism

Key words

CaaX proteins; Ras; Ras converting enzyme; cancer; proteases

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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Endopeptidases / Oxyquinoline / Endoplasmic Reticulum / Proteolysis / Neoplasm Proteins / Neoplasms Limits: Animals / Humans Language: En Journal: Crit Rev Biochem Mol Biol Journal subject: BIOLOGIA MOLECULAR / BIOQUIMICA Year: 2018 Type: Article Affiliation country: United Arab Emirates

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