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P300 Acetyltransferase Mediates Stiffness-Induced Activation of Hepatic Stellate Cells Into Tumor-Promoting Myofibroblasts.
Dou, Changwei; Liu, Zhikui; Tu, Kangsheng; Zhang, Hongbin; Chen, Chen; Yaqoob, Usman; Wang, Yuanguo; Wen, Jialing; van Deursen, Jan; Sicard, Delphine; Tschumperlin, Daniel; Zou, Hongzhi; Huang, Wei-Chien; Urrutia, Raul; Shah, Vijay H; Kang, Ningling.
Affiliation
  • Dou C; GI Research Unit and Cancer Cell Biology Program, Mayo Clinic, Rochester, Minnesota; Department of Hepatobiliary Surgery, 1st Affiliated Hospital of Xi'an Jiaotong University, Xi'an, China; Department of Hepatobiliary Surgery, Zhejiang Provincial People's Hospital, Hangzhou, China.
  • Liu Z; GI Research Unit and Cancer Cell Biology Program, Mayo Clinic, Rochester, Minnesota; Department of Hepatobiliary Surgery, 1st Affiliated Hospital of Xi'an Jiaotong University, Xi'an, China.
  • Tu K; Department of Hepatobiliary Surgery, 1st Affiliated Hospital of Xi'an Jiaotong University, Xi'an, China; Tumor Microenvironment and Metastasis, Hormel Institute, University of Minnesota, Minneapolis, Minnesota.
  • Zhang H; Tumor Microenvironment and Metastasis, Hormel Institute, University of Minnesota, Minneapolis, Minnesota.
  • Chen C; Tumor Microenvironment and Metastasis, Hormel Institute, University of Minnesota, Minneapolis, Minnesota.
  • Yaqoob U; GI Research Unit and Cancer Cell Biology Program, Mayo Clinic, Rochester, Minnesota.
  • Wang Y; Tumor Microenvironment and Metastasis, Hormel Institute, University of Minnesota, Minneapolis, Minnesota.
  • Wen J; Tumor Microenvironment and Metastasis, Hormel Institute, University of Minnesota, Minneapolis, Minnesota.
  • van Deursen J; Department of Biochemistry and Molecular Biology, Mayo Clinic, Rochester, Minnesota.
  • Sicard D; Department of Physiology and Biomedical Engineering, Mayo Clinic, Rochester, Minnesota.
  • Tschumperlin D; Department of Physiology and Biomedical Engineering, Mayo Clinic, Rochester, Minnesota.
  • Zou H; Guangdong Institute of Gastroenterology, 6th Affiliated Hospital, Sun Yat-sen University, Guangzhou, China.
  • Huang WC; Graduate Institute of Biomedical Science, China Medical University, Taiwan, R.O.C.
  • Urrutia R; GI Research Unit and Cancer Cell Biology Program, Mayo Clinic, Rochester, Minnesota.
  • Shah VH; GI Research Unit and Cancer Cell Biology Program, Mayo Clinic, Rochester, Minnesota. Electronic address: Shah.Vijay@Mayo.edu.
  • Kang N; Tumor Microenvironment and Metastasis, Hormel Institute, University of Minnesota, Minneapolis, Minnesota. Electronic address: nkang@hi.umn.edu.
Gastroenterology ; 154(8): 2209-2221.e14, 2018 06.
Article in En | MEDLINE | ID: mdl-29454793
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Cell Transformation, Neoplastic / Carcinoma, Hepatocellular / E1A-Associated p300 Protein / Hepatic Stellate Cells / Myofibroblasts / Liver Neoplasms Limits: Animals / Humans Language: En Journal: Gastroenterology Year: 2018 Type: Article Affiliation country: China
Fulltext
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Cell Transformation, Neoplastic / Carcinoma, Hepatocellular / E1A-Associated p300 Protein / Hepatic Stellate Cells / Myofibroblasts / Liver Neoplasms Limits: Animals / Humans Language: En Journal: Gastroenterology Year: 2018 Type: Article Affiliation country: China