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CRISPR/cas9 mediated knockout of an intergenic variant rs6927172 identified IL-20RA as a new risk gene for multiple autoimmune diseases.
Wu, Jianfeng; Yang, Sirui; Yu, Di; Gao, Wenjing; Liu, Xianjun; Zhang, Kun; Fu, Xueqi; Bao, Wanguo; Zhang, Kaiyu; Yu, Jiaao; Sun, Liankun; Wang, Shaofeng.
Affiliation
  • Wu J; The Institute of Epigenetic Medicine, The First Hospital of Jilin University, Changchun, China.
  • Yang S; College of Basic Medicine, The Jilin University, Changchun, China.
  • Yu D; The Institute of Pediatrics, The First Hospital of Jilin University, Changchun, China.
  • Gao W; The Institute of Epigenetic Medicine, The First Hospital of Jilin University, Changchun, China.
  • Liu X; The Institute of Epigenetic Medicine, The First Hospital of Jilin University, Changchun, China.
  • Zhang K; The Institute of Epigenetic Medicine, The First Hospital of Jilin University, Changchun, China.
  • Fu X; The Center of Research, The Second Hospital of Jilin University, Changchun, China.
  • Bao W; The College of Life Sciences, The Jilin University, Changchun, China.
  • Zhang K; Department of Infectious Diseases, The First Hospital of Jilin University, Changchun, China.
  • Yu J; Department of Infectious Diseases, The First Hospital of Jilin University, Changchun, China.
  • Sun L; Department of Burn Surgery, The First Hospital of Jilin University, Changchun, China.
  • Wang S; College of Basic Medicine, The Jilin University, Changchun, China.
Genes Immun ; 20(2): 103-111, 2019 02.
Article in En | MEDLINE | ID: mdl-29483615
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Autoimmune Diseases / Receptors, Interleukin / Polymorphism, Single Nucleotide Type of study: Etiology_studies / Prognostic_studies / Risk_factors_studies Limits: Humans Language: En Journal: Genes Immun Journal subject: ALERGIA E IMUNOLOGIA / BIOLOGIA MOLECULAR Year: 2019 Type: Article Affiliation country: China
Fulltext
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Autoimmune Diseases / Receptors, Interleukin / Polymorphism, Single Nucleotide Type of study: Etiology_studies / Prognostic_studies / Risk_factors_studies Limits: Humans Language: En Journal: Genes Immun Journal subject: ALERGIA E IMUNOLOGIA / BIOLOGIA MOLECULAR Year: 2019 Type: Article Affiliation country: China