Recent progress in Lynch syndrome and other familial colorectal cancer syndromes.

Boland, Patrick M; Yurgelun, Matthew B; Boland, C Richard

Boland, Patrick M; Yurgelun, Matthew B; Boland, C Richard.

Affiliation

Boland PM; Assistant Professor, Department of Medicine, Roswell Park Cancer Institute, Buffalo, NY.
Yurgelun MB; Assistant Professor of Medicine, Dana-Farber Cancer Institute and Harvard Medical School, Boston, MA.
Boland CR; Professor, Department of Medicine, University of California at San Diego School of Medicine, San Diego, CA.

CA Cancer J Clin ; 68(3): 217-231, 2018 05.

Article in En | MEDLINE | ID: mdl-29485237

Subject(s)

Colorectal Neoplasms, Hereditary Nonpolyposis/genetics; Colorectal Neoplasms, Hereditary Nonpolyposis/therapy; Adenoma/pathology; Cell Transformation, Neoplastic; Chemoprevention; Chemotherapy, Adjuvant; Colectomy; Colonoscopy; Colorectal Neoplasms/pathology; Colorectal Neoplasms, Hereditary Nonpolyposis/epidemiology; DNA Mutational Analysis; Genetic Testing; Germ-Line Mutation; Humans; Sequence Analysis, DNA/methods

Key words

DNA mismatch repair; Lynch syndrome; adenomatous polyposis (APC) gene; familial colorectal cancer; genetic testing; germline mutations; immune checkpoint therapy

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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Colorectal Neoplasms, Hereditary Nonpolyposis Limits: Humans Language: En Journal: CA Cancer J Clin Year: 2018 Type: Article

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