Structural Basis for Superoxide Activation of Flavobacterium johnsoniae Class I Ribonucleotide Reductase and for Radical Initiation by Its Dimanganese Cofactor.

Rose, Hannah R; Ghosh, Manas K; Maggiolo, Ailiena O; Pollock, Christopher J; Blaesi, Elizabeth J; Hajj, Viviane; Wei, Yifeng; Rajakovich, Lauren J; Chang, Wei-Chen; Han, Yilin; Hajj, Mariana; Krebs, Carsten; Silakov, Alexey; Pandelia, Maria-Eirini; Bollinger, J Martin; Boal, Amie K

Rose, Hannah R; Ghosh, Manas K; Maggiolo, Ailiena O; Pollock, Christopher J; Blaesi, Elizabeth J; Hajj, Viviane; Wei, Yifeng; Rajakovich, Lauren J; Chang, Wei-Chen; Han, Yilin; Hajj, Mariana; Krebs, Carsten; Silakov, Alexey; Pandelia, Maria-Eirini; Bollinger, J Martin; Boal, Amie K.

Affiliation

Wei Y; Department of Chemistry , Massachusetts Institute of Technology , Cambridge , Massachusetts 02139 , United States.
Pandelia ME; Department of Biochemistry , Brandeis University , Waltham , Massachusetts 02454 , United States.

Biochemistry ; 57(18): 2679-2693, 2018 05 08.

Article in En | MEDLINE | ID: mdl-29609464

Subject(s)

Flavoproteins/chemistry; Manganese/chemistry; Ribonucleotide Reductases/chemistry; Superoxides/chemistry; Catalysis; Catalytic Domain; Flavobacterium/chemistry; Flavobacterium/enzymology; Flavoproteins/metabolism; Iron/chemistry; Oxidation-Reduction; Oxygen/chemistry; Ribonucleotide Reductases/classification; Ribonucleotide Reductases/metabolism; Tyrosine/chemistry

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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Ribonucleotide Reductases / Superoxides / Flavoproteins / Manganese Language: En Journal: Biochemistry Year: 2018 Type: Article

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