Prospective assessment of the predictive value of the BRCA1 gene status in sarcoma patients treated with trabectedin: an updated analysis of the EORTC 62091 trial.

Italiano, Antoine; Touati, Nathan; Litière, Saskia; Collin, Françoise; Pourquier, Philippe; Gronchi, Alessandro

Italiano, Antoine; Touati, Nathan; Litière, Saskia; Collin, Françoise; Pourquier, Philippe; Gronchi, Alessandro.

Affiliation

Italiano A; Institut Bergonié, Bordeaux, France.
Touati N; INSERM U1218, Bordeaux, France.
Litière S; European Organization for Research and Treatment of Cancer, Brussels, Belgium.
Collin F; European Organization for Research and Treatment of Cancer, Brussels, Belgium.
Pourquier P; Centre Georges-François Leclerc, Dijon, France.
Gronchi A; Institute of Cancer Research of Montpellier, Montpellier, France.

Cancer Med ; 7(5): 1575-1577, 2018 05.

Article in En | MEDLINE | ID: mdl-29656586

Subject(s)

Antineoplastic Agents, Alkylating/therapeutic use; BRCA1 Protein/genetics; Sarcoma/drug therapy; Trabectedin/therapeutic use; Female; Genotype; Humans; Male; Predictive Value of Tests; Prospective Studies; Sarcoma/genetics; Treatment Outcome

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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Sarcoma / Antineoplastic Agents, Alkylating / BRCA1 Protein / Trabectedin Type of study: Clinical_trials / Observational_studies / Prognostic_studies / Risk_factors_studies Limits: Female / Humans / Male Language: En Journal: Cancer Med Year: 2018 Type: Article Affiliation country: France

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