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Distinct in vivo roles of secreted APP ectodomain variants APPsα and APPsß in regulation of spine density, synaptic plasticity, and cognition.
Richter, Max C; Ludewig, Susann; Winschel, Alex; Abel, Tobias; Bold, Charlotte; Salzburger, Leonie R; Klein, Susanne; Han, Kang; Weyer, Sascha W; Fritz, Ann-Kristina; Laube, Bodo; Wolfer, David P; Buchholz, Christian J; Korte, Martin; Müller, Ulrike C.
Affiliation
  • Richter MC; Institute of Pharmacy and Molecular Biotechnology (IPMB), Ruprecht-Karls University Heidelberg, Heidelberg, Germany.
  • Ludewig S; Zoological Institute, Division of Cellular Neurobiology, TU Braunschweig, Braunschweig, Germany.
  • Winschel A; Department of Biology, Neurophysiology und Neurosensory Systems, TU Darmstadt, Darmstadt, Germany.
  • Abel T; Paul-Ehrlich-Institut (PEI), Langen, Germany.
  • Bold C; Institute of Pharmacy and Molecular Biotechnology (IPMB), Ruprecht-Karls University Heidelberg, Heidelberg, Germany.
  • Salzburger LR; Zoological Institute, Division of Cellular Neurobiology, TU Braunschweig, Braunschweig, Germany.
  • Klein S; Institute of Pharmacy and Molecular Biotechnology (IPMB), Ruprecht-Karls University Heidelberg, Heidelberg, Germany.
  • Han K; Institute of Pharmacy and Molecular Biotechnology (IPMB), Ruprecht-Karls University Heidelberg, Heidelberg, Germany.
  • Weyer SW; Institute of Pharmacy and Molecular Biotechnology (IPMB), Ruprecht-Karls University Heidelberg, Heidelberg, Germany.
  • Fritz AK; Institute of Anatomy, University of Zurich, Zurich, Switzerland.
  • Laube B; Institute of Human Movements Sciences and Sport, ETH Zurich, Zurich, Switzerland.
  • Wolfer DP; Department of Biology, Neurophysiology und Neurosensory Systems, TU Darmstadt, Darmstadt, Germany.
  • Buchholz CJ; Institute of Anatomy, University of Zurich, Zurich, Switzerland.
  • Korte M; Institute of Human Movements Sciences and Sport, ETH Zurich, Zurich, Switzerland.
  • Müller UC; Paul-Ehrlich-Institut (PEI), Langen, Germany.
EMBO J ; 37(11)2018 06 01.
Article in En | MEDLINE | ID: mdl-29661886

Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Amyloid beta-Protein Precursor / Cognition / Alzheimer Disease / Neuronal Plasticity Limits: Animals / Humans Language: En Journal: EMBO J Year: 2018 Type: Article Affiliation country: Germany

Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Amyloid beta-Protein Precursor / Cognition / Alzheimer Disease / Neuronal Plasticity Limits: Animals / Humans Language: En Journal: EMBO J Year: 2018 Type: Article Affiliation country: Germany