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Structural basis of ligand binding modes at the neuropeptide Y Y1 receptor.
Yang, Zhenlin; Han, Shuo; Keller, Max; Kaiser, Anette; Bender, Brian J; Bosse, Mathias; Burkert, Kerstin; Kögler, Lisa M; Wifling, David; Bernhardt, Guenther; Plank, Nicole; Littmann, Timo; Schmidt, Peter; Yi, Cuiying; Li, Beibei; Ye, Sheng; Zhang, Rongguang; Xu, Bo; Larhammar, Dan; Stevens, Raymond C; Huster, Daniel; Meiler, Jens; Zhao, Qiang; Beck-Sickinger, Annette G; Buschauer, Armin; Wu, Beili.
Affiliation
  • Yang Z; Chinese Academy of Sciences Key Laboratory of Receptor Research, Shanghai Institute of Materia Medica, Chinese Academy of Sciences, Shanghai, China.
  • Han S; State Key Laboratory of Drug Research, Shanghai Institute of Materia Medica, Chinese Academy of Sciences, Shanghai, China.
  • Keller M; Chinese Academy of Sciences Key Laboratory of Receptor Research, Shanghai Institute of Materia Medica, Chinese Academy of Sciences, Shanghai, China.
  • Kaiser A; National Laboratory of Biomacromolecules, Institute of Biophysics, Chinese Academy of Sciences, Beijing, China.
  • Bender BJ; Pharmaceutical/Medicinal Chemistry II, Institute of Pharmacy, University of Regensburg, Regensburg, Germany. max.keller@chemie.uni-regensburg.de.
  • Bosse M; Institute of Biochemistry, Faculty of Life Sciences, Leipzig University, Leipzig, Germany.
  • Burkert K; Department of Pharmacology, Center for Structural Biology, Vanderbilt University, Nashville, TN, USA.
  • Kögler LM; Institute for Medical Physics and Biophysics, Leipzig University, Leipzig, Germany.
  • Wifling D; Institute of Biochemistry, Faculty of Life Sciences, Leipzig University, Leipzig, Germany.
  • Bernhardt G; Institute of Biochemistry, Faculty of Life Sciences, Leipzig University, Leipzig, Germany.
  • Plank N; Pharmaceutical/Medicinal Chemistry II, Institute of Pharmacy, University of Regensburg, Regensburg, Germany.
  • Littmann T; Pharmaceutical/Medicinal Chemistry II, Institute of Pharmacy, University of Regensburg, Regensburg, Germany.
  • Schmidt P; Pharmaceutical/Medicinal Chemistry II, Institute of Pharmacy, University of Regensburg, Regensburg, Germany.
  • Yi C; Pharmaceutical/Medicinal Chemistry II, Institute of Pharmacy, University of Regensburg, Regensburg, Germany.
  • Li B; Institute for Medical Physics and Biophysics, Leipzig University, Leipzig, Germany.
  • Ye S; Chinese Academy of Sciences Key Laboratory of Receptor Research, Shanghai Institute of Materia Medica, Chinese Academy of Sciences, Shanghai, China.
  • Zhang R; Chinese Academy of Sciences Key Laboratory of Receptor Research, Shanghai Institute of Materia Medica, Chinese Academy of Sciences, Shanghai, China.
  • Xu B; University of Chinese Academy of Sciences, Beijing, China.
  • Larhammar D; National Laboratory of Biomacromolecules, Institute of Biophysics, Chinese Academy of Sciences, Beijing, China.
  • Stevens RC; National Laboratory of Biomacromolecules, Institute of Biophysics, Chinese Academy of Sciences, Beijing, China.
  • Huster D; National Center for Protein Science Shanghai, Institute of Biochemistry and Cell Biology, Shanghai Institutes for Biological Sciences, Chinese Academy of Sciences, Shanghai, China.
  • Meiler J; Department of Neuroscience, Science for Life Laboratory, Uppsala University, Uppsala, Sweden.
  • Zhao Q; Department of Neuroscience, Science for Life Laboratory, Uppsala University, Uppsala, Sweden.
  • Beck-Sickinger AG; iHuman Institute, ShanghaiTech University, Shanghai, China.
  • Buschauer A; School of Life Science and Technology, ShanghaiTech University, Shanghai, China.
  • Wu B; Institute for Medical Physics and Biophysics, Leipzig University, Leipzig, Germany.
Nature ; 556(7702): 520-524, 2018 04.
Article in En | MEDLINE | ID: mdl-29670288
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Phenylurea Compounds / Arginine / Neuropeptide Y / Dihydropyridines / Receptors, Neuropeptide Y / Diphenylacetic Acids Limits: Humans Language: En Journal: Nature Year: 2018 Type: Article Affiliation country: China
Fulltext
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Phenylurea Compounds / Arginine / Neuropeptide Y / Dihydropyridines / Receptors, Neuropeptide Y / Diphenylacetic Acids Limits: Humans Language: En Journal: Nature Year: 2018 Type: Article Affiliation country: China