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Phosphodiesterase 4 and 7 inhibitors produce protective effects against high glucose-induced neurotoxicity in PC12 cells via modulation of the oxidative stress, apoptosis and inflammation pathways.
Namazi Sarvestani, Nazanin; Saberi Firouzi, Saeedeh; Falak, Reza; Karimi, Mohammad Yahya; Davoodzadeh Gholami, Mohammad; Rangbar, Akram; Hosseini, Asieh.
Affiliation
  • Namazi Sarvestani N; Department of Animal Biology, School of Biology, Department of Science, University of Tehran, Tehran, Iran.
  • Saberi Firouzi S; Department of Pharmacology, Faculty of Medicine, Tehran University of Medical Sciences, Tehran, Iran.
  • Falak R; Department of Immunology, School of Medicine, Iran University of Medical Sciences, Tehran, Iran.
  • Karimi MY; Razi Drug Research Center, Iran University of Medical Sciences, Tehran, Iran.
  • Davoodzadeh Gholami M; Department of Immunology, School of Medicine, Iran University of Medical Sciences, Tehran, Iran.
  • Rangbar A; Department of Toxicology and Pharmacology, School of Pharmacy, Hamadan University of Medical Sciences, Hamadan, Iran.
  • Hosseini A; Razi Drug Research Center, Iran University of Medical Sciences, Tehran, Iran. hoseini.as@iums.ac.ir.
Metab Brain Dis ; 33(4): 1293-1306, 2018 08.
Article in En | MEDLINE | ID: mdl-29713919
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Phosphodiesterase Inhibitors / Apoptosis / Oxidative Stress / Neuroprotective Agents / Glucose / Inflammation Type of study: Prognostic_studies Limits: Animals Language: En Journal: Metab Brain Dis Journal subject: CEREBRO / METABOLISMO Year: 2018 Type: Article Affiliation country: Iran
Fulltext
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Phosphodiesterase Inhibitors / Apoptosis / Oxidative Stress / Neuroprotective Agents / Glucose / Inflammation Type of study: Prognostic_studies Limits: Animals Language: En Journal: Metab Brain Dis Journal subject: CEREBRO / METABOLISMO Year: 2018 Type: Article Affiliation country: Iran