Insights into catalysis and function of phosphoribosyl-linked serine ubiquitination.

Kalayil, Sissy; Bhogaraju, Sagar; Bonn, Florian; Shin, Donghyuk; Liu, Yaobin; Gan, Ninghai; Basquin, Jérôme; Grumati, Paolo; Luo, Zhao-Qing; Dikic, Ivan

Kalayil, Sissy; Bhogaraju, Sagar; Bonn, Florian; Shin, Donghyuk; Liu, Yaobin; Gan, Ninghai; Basquin, Jérôme; Grumati, Paolo; Luo, Zhao-Qing; Dikic, Ivan.

Affiliation

Kalayil S; Institute of Biochemistry II, Goethe University Frankfurt - Medical Faculty, University Hospital, Frankfurt am Main, Germany.
Bhogaraju S; Buchmann Institute for Molecular Life Sciences, Goethe University Frankfurt, Frankfurt am Main, Germany.
Bonn F; Institute of Biochemistry II, Goethe University Frankfurt - Medical Faculty, University Hospital, Frankfurt am Main, Germany.
Shin D; Buchmann Institute for Molecular Life Sciences, Goethe University Frankfurt, Frankfurt am Main, Germany.
Liu Y; Institute of Biochemistry II, Goethe University Frankfurt - Medical Faculty, University Hospital, Frankfurt am Main, Germany.
Gan N; Institute of Biochemistry II, Goethe University Frankfurt - Medical Faculty, University Hospital, Frankfurt am Main, Germany.
Basquin J; Buchmann Institute for Molecular Life Sciences, Goethe University Frankfurt, Frankfurt am Main, Germany.
Grumati P; Institute of Biochemistry II, Goethe University Frankfurt - Medical Faculty, University Hospital, Frankfurt am Main, Germany.
Luo ZQ; Buchmann Institute for Molecular Life Sciences, Goethe University Frankfurt, Frankfurt am Main, Germany.
Dikic I; Purdue Institute of Immunology, Inflammation and Infectious Diseases and Department of Biological Sciences, Purdue University, West Lafayette, IN, USA.

Nature ; 557(7707): 734-738, 2018 05.

Article in En | MEDLINE | ID: mdl-29795347

Subject(s)

Biocatalysis; Legionella pneumophila/enzymology; Membrane Proteins/chemistry; Membrane Proteins/metabolism; Serine/metabolism; Ubiquitination; ADP Ribose Transferases/chemistry; ADP Ribose Transferases/metabolism; Adenosine Diphosphate/metabolism; Amino Acid Sequence; Bacterial Proteins; Binding Sites; Catalytic Domain; Crystallography, X-Ray; Legionella pneumophila/genetics; Legionella pneumophila/pathogenicity; Legionnaires' Disease/microbiology; Membrane Proteins/genetics; Models, Molecular; Phosphoric Diester Hydrolases/chemistry; Phosphoric Diester Hydrolases/metabolism; Protein Structure, Secondary; Substrate Specificity; Ubiquitin/metabolism

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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Serine / Legionella pneumophila / Ubiquitination / Biocatalysis / Membrane Proteins Type of study: Prognostic_studies Language: En Journal: Nature Year: 2018 Type: Article Affiliation country: Germany

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