Impaired Immune Response to Primary but Not to Booster Vaccination Against Hepatitis B in Older Adults.

Weinberger, Birgit; Haks, Mariëlle C; de Paus, Roelof A; Ottenhoff, Tom H M; Bauer, Tanja; Grubeck-Loebenstein, Beatrix

Weinberger, Birgit; Haks, Mariëlle C; de Paus, Roelof A; Ottenhoff, Tom H M; Bauer, Tanja; Grubeck-Loebenstein, Beatrix.

Affiliation

Weinberger B; Institute for Biomedical Aging Research, Universität Innsbruck, Innsbruck, Austria.
Haks MC; Department of Infectious Diseases, Leiden University Medical Center, Leiden, Netherlands.
de Paus RA; Department of Infectious Diseases, Leiden University Medical Center, Leiden, Netherlands.
Ottenhoff THM; Department of Infectious Diseases, Leiden University Medical Center, Leiden, Netherlands.
Bauer T; Institute of Virology, Technische Universität München/Helmholtz Zentrum München, Munich, Germany.
Grubeck-Loebenstein B; Institute for Biomedical Aging Research, Universität Innsbruck, Innsbruck, Austria.

Front Immunol ; 9: 1035, 2018.

Article in En | MEDLINE | ID: mdl-29868000

Subject(s)

Hepatitis B Vaccines/immunology; Hepatitis C Antibodies/blood; Immunization, Secondary; Immunization; Immunogenicity, Vaccine; Adult; Age Factors; Aged; Cytokines/genetics; Female; Healthy Volunteers; Hepatitis B; Hepatitis B Vaccines/administration & dosage; Humans; Immunologic Memory; Inflammasomes/genetics; Male; Middle Aged; Transcriptome; Young Adult

Key words

booster vaccination; elderly; gene expression profiling; hepatitis B virus; primary vaccination; vaccine

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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Immunization, Secondary / Immunization / Hepatitis B Vaccines / Hepatitis C Antibodies / Immunogenicity, Vaccine Type of study: Prognostic_studies Limits: Adult / Aged / Female / Humans / Male / Middle aged Language: En Journal: Front Immunol Year: 2018 Type: Article Affiliation country: Austria

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