Lack of Effect of Sodium Benzoate at Reported Clinical Therapeutic Concentration on d-Alanine Metabolism in Dogs.

Popiolek, Michael; Tierney, Brendan; Steyn, Stefanus J; DeVivo, Michael

Popiolek, Michael; Tierney, Brendan; Steyn, Stefanus J; DeVivo, Michael.

ACS Chem Neurosci ; 9(11): 2832-2837, 2018 11 21.

Article in En | MEDLINE | ID: mdl-29893546

Subject(s)

Alanine/drug effects; Sodium Benzoate/pharmacology; Alanine/metabolism; Alzheimer Disease/drug therapy; Alzheimer Disease/metabolism; Animals; Benzoic Acid/cerebrospinal fluid; Cognitive Dysfunction/drug therapy; Cognitive Dysfunction/metabolism; D-Amino-Acid Oxidase/antagonists & inhibitors; Dogs; Humans; Receptors, N-Methyl-D-Aspartate/agonists; Schizophrenia/drug therapy; Schizophrenia/metabolism; Treatment Outcome

Key words

Alzheimer's disease; Sodium benzoate; d-alanine; d-amino acid oxidase; in vivo efficacy; schizophrenia

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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Sodium Benzoate / Alanine Limits: Animals / Humans Language: En Journal: ACS Chem Neurosci Year: 2018 Type: Article

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