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Trehalose reduces retinal degeneration, neuroinflammation and storage burden caused by a lysosomal hydrolase deficiency.
Lotfi, Parisa; Tse, Dennis Y; Di Ronza, Alberto; Seymour, Michelle L; Martano, Giuseppe; Cooper, Jonathan D; Pereira, Fred A; Passafaro, Maria; Wu, Samuel M; Sardiello, Marco.
Affiliation
  • Lotfi P; a Department of Molecular and Human Genetics , Baylor College of Medicine, Jan and Dan Duncan Neurological Research Institute at Texas Children's Hospital , Houston , TX , USA.
  • Tse DY; b Department of Ophthalmology , Cullen Eye Institute, Baylor College of Medicine , Houston , TX , USA.
  • Di Ronza A; c School of Optometry , The Hong Kong Polytechnic University , Kowloon , Hong Kong.
  • Seymour ML; a Department of Molecular and Human Genetics , Baylor College of Medicine, Jan and Dan Duncan Neurological Research Institute at Texas Children's Hospital , Houston , TX , USA.
  • Martano G; d Huffington Center on Aging, Department of Molecular and Cellular Biology , Baylor College of Medicine , Houston , TX , USA.
  • Cooper JD; e Department of Otolaryngology-Head & Neck Surgery , Baylor College of Medicine , Houston , TX , USA.
  • Pereira FA; f CNR Institute of Neuroscience , Milan , Italy.
  • Passafaro M; g Department of Basic and Clinical Neuroscience , Maurice Wohl Clinical Neuroscience Institute, Institute of Psychiatry, Psychology and Neuroscience , Kings College London , London , UK.
  • Wu SM; h Department of Pediatrics, Los Angeles Biomedical Research Institute at Harbor-UCLA Medical Center , David Geffen School of Medicine, UCLA , Torrance , CA , USA.
  • Sardiello M; d Huffington Center on Aging, Department of Molecular and Cellular Biology , Baylor College of Medicine , Houston , TX , USA.
Autophagy ; 14(8): 1419-1434, 2018.
Article in En | MEDLINE | ID: mdl-29916295
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Retinal Degeneration / Acetylglucosaminidase / Trehalose / Brain / Disease Progression / Inflammation Type of study: Prognostic_studies Limits: Animals Language: En Journal: Autophagy Year: 2018 Type: Article Affiliation country: United States
Fulltext
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Retinal Degeneration / Acetylglucosaminidase / Trehalose / Brain / Disease Progression / Inflammation Type of study: Prognostic_studies Limits: Animals Language: En Journal: Autophagy Year: 2018 Type: Article Affiliation country: United States