RBPJ binds to consensus and methylated cis elements within phased nucleosomes and controls gene expression in human aortic smooth muscle cells in cooperation with SRF.

Rozenberg, Julian M; Taylor, Joan M; Mack, Christopher P

Rozenberg, Julian M; Taylor, Joan M; Mack, Christopher P.

Affiliation

Rozenberg JM; Department of Pathology, University of North Carolina, Chapel Hill, NC 27599, USA.
Taylor JM; Department of Pathology, University of North Carolina, Chapel Hill, NC 27599, USA.
Mack CP; Department of Pathology, University of North Carolina, Chapel Hill, NC 27599, USA.

Nucleic Acids Res ; 46(16): 8232-8244, 2018 09 19.

Article in En | MEDLINE | ID: mdl-29931229

Subject(s)

Enhancer Elements, Genetic/genetics; Gene Expression Regulation; Immunoglobulin J Recombination Signal Sequence-Binding Protein/genetics; Myocytes, Smooth Muscle/metabolism; Nucleosomes/genetics; Serum Response Factor/genetics; Aorta/cytology; Base Sequence; Binding Sites/genetics; Cell Differentiation/genetics; Cell Line; DNA Methylation; Humans; Immunoglobulin J Recombination Signal Sequence-Binding Protein/metabolism; Nucleosomes/metabolism; Protein Binding; Serum Response Factor/metabolism

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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Nucleosomes / Gene Expression Regulation / Enhancer Elements, Genetic / Serum Response Factor / Myocytes, Smooth Muscle / Immunoglobulin J Recombination Signal Sequence-Binding Protein Type of study: Prognostic_studies Limits: Humans Language: En Journal: Nucleic Acids Res Year: 2018 Type: Article Affiliation country: United States

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