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High-Throughput Functional Analysis Distinguishes Pathogenic, Nonpathogenic, and Compensatory Transcriptional Changes in Neurodegeneration.
Al-Ramahi, Ismael; Lu, Boxun; Di Paola, Simone; Pang, Kaifang; de Haro, Maria; Peluso, Ivana; Gallego-Flores, Tatiana; Malik, Nazish T; Erikson, Kelly; Bleiberg, Benjamin A; Avalos, Matthew; Fan, George; Rivers, Laura Elizabeth; Laitman, Andrew M; Diaz-García, Javier R; Hild, Marc; Palacino, James; Liu, Zhandong; Medina, Diego L; Botas, Juan.
Affiliation
  • Al-Ramahi I; Department of Molecular and Human Genetics, Baylor College of Medicine, Houston, TX 77030, USA; Jan and Dan Duncan Neurological Research Institute at Texas Children's Hospital, Houston, TX 77030, USA.
  • Lu B; State Key Laboratory of Medical Neurobiology, Collaborative Innovation Center for Brain Science, School of Life Sciences, Fudan University, Shanghai, China.
  • Di Paola S; Telethon Institute of Genetics and Medicine (TIGEM), Pozzuoli, Italy.
  • Pang K; Jan and Dan Duncan Neurological Research Institute at Texas Children's Hospital, Houston, TX 77030, USA.
  • de Haro M; Department of Molecular and Human Genetics, Baylor College of Medicine, Houston, TX 77030, USA; Jan and Dan Duncan Neurological Research Institute at Texas Children's Hospital, Houston, TX 77030, USA.
  • Peluso I; Telethon Institute of Genetics and Medicine (TIGEM), Pozzuoli, Italy.
  • Gallego-Flores T; Department of Molecular and Human Genetics, Baylor College of Medicine, Houston, TX 77030, USA; Jan and Dan Duncan Neurological Research Institute at Texas Children's Hospital, Houston, TX 77030, USA.
  • Malik NT; Department of Molecular and Human Genetics, Baylor College of Medicine, Houston, TX 77030, USA; Jan and Dan Duncan Neurological Research Institute at Texas Children's Hospital, Houston, TX 77030, USA.
  • Erikson K; Department of Molecular and Human Genetics, Baylor College of Medicine, Houston, TX 77030, USA; Jan and Dan Duncan Neurological Research Institute at Texas Children's Hospital, Houston, TX 77030, USA.
  • Bleiberg BA; Department of Molecular and Human Genetics, Baylor College of Medicine, Houston, TX 77030, USA; Jan and Dan Duncan Neurological Research Institute at Texas Children's Hospital, Houston, TX 77030, USA.
  • Avalos M; Department of Molecular and Human Genetics, Baylor College of Medicine, Houston, TX 77030, USA; Jan and Dan Duncan Neurological Research Institute at Texas Children's Hospital, Houston, TX 77030, USA.
  • Fan G; Department of Molecular and Human Genetics, Baylor College of Medicine, Houston, TX 77030, USA; Jan and Dan Duncan Neurological Research Institute at Texas Children's Hospital, Houston, TX 77030, USA.
  • Rivers LE; Department of Molecular and Human Genetics, Baylor College of Medicine, Houston, TX 77030, USA; Jan and Dan Duncan Neurological Research Institute at Texas Children's Hospital, Houston, TX 77030, USA.
  • Laitman AM; Jan and Dan Duncan Neurological Research Institute at Texas Children's Hospital, Houston, TX 77030, USA.
  • Diaz-García JR; Department of Molecular and Human Genetics, Baylor College of Medicine, Houston, TX 77030, USA; Jan and Dan Duncan Neurological Research Institute at Texas Children's Hospital, Houston, TX 77030, USA.
  • Hild M; Novartis Institutes for Biomedical Research, Cambridge, MA, USA.
  • Palacino J; Novartis Institutes for Biomedical Research, Cambridge, MA, USA.
  • Liu Z; Jan and Dan Duncan Neurological Research Institute at Texas Children's Hospital, Houston, TX 77030, USA.
  • Medina DL; Telethon Institute of Genetics and Medicine (TIGEM), Pozzuoli, Italy.
  • Botas J; Department of Molecular and Human Genetics, Baylor College of Medicine, Houston, TX 77030, USA; Jan and Dan Duncan Neurological Research Institute at Texas Children's Hospital, Houston, TX 77030, USA. Electronic address: jbotas@bcm.edu.
Cell Syst ; 7(1): 28-40.e4, 2018 07 25.
Article in En | MEDLINE | ID: mdl-29936182
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Huntington Disease / High-Throughput Screening Assays Limits: Animals / Female / Humans / Male Language: En Journal: Cell Syst Year: 2018 Type: Article Affiliation country: United States
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Huntington Disease / High-Throughput Screening Assays Limits: Animals / Female / Humans / Male Language: En Journal: Cell Syst Year: 2018 Type: Article Affiliation country: United States