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Gender and Racial Disparities in Initial Hemodialysis Access and Outcomes in Incident End-Stage Renal Disease Patients.
Shah, Silvi; Leonard, Anthony C; Meganathan, Karthikeyan; Christianson, Annette L; Thakar, Charuhas V.
Affiliation
  • Shah S; Division of Nephrology Kidney C.A.R.E. Program, University of Cincinnati, Cincinnati, Ohio, USA.
  • Leonard AC; Department of Family and Community Medicine, University of Cincinnati, Cincinnati, Ohio, USA.
  • Meganathan K; Department of Biomedical Informatics, University of Cincinnati, Cincinnati, Ohio, USA.
  • Christianson AL; Department of Biomedical Informatics, University of Cincinnati, Cincinnati, Ohio, USA.
  • Thakar CV; Division of Nephrology Kidney C.A.R.E. Program, University of Cincinnati, Cincinnati, Ohio, USA.
Am J Nephrol ; 48(1): 4-14, 2018.
Article in En | MEDLINE | ID: mdl-29990994
BACKGROUND: Arteriovenous (AV) access confers survival benefits over central venous catheters (CVC) in hemodialysis patients. Although chronic kidney disease disproportionately affects women and racial minorities, disparities in the -utilization of hemodialysis access across Asians, Native Americans, Hispanics, blacks, and whites among males and females after accounting for pre-dialysis health are not well studied. METHODS: We evaluated 885,699 patients with end-stage renal disease who initiated hemodialysis between January 1, 2004 and December 31, 2014 using the US Renal Data System. Multivariable logistic regression models -adjusted for pre-dialysis health were used to test the associations between gender and race on type of vascular access (AV access vs. CVC, and AV fistula vs. AV graft) at hemodialysis initiation as primary outcome, and on 1-year mortality as a secondary outcome. RESULTS: Mean age was 65 ± 14 years. Females were less likely to use AV access for hemodialysis initiation than were males (OR 0.85; 95% CI 0.84-0.86). Compared to whites, adjusted odds of AV access for hemodialysis initiation were higher in blacks (OR 1.08; 95% CI 1.07-1.70), Asians (OR 1.11; 95% CI 1.07-1.14); and lower in Hispanics (OR 0.89; 95% CI 0.87-0.90). There was no -significant difference in mortality between males and females. Compared to whites, 1-year adjusted mortality was lower in Asians (OR 0.55; 95% CI 0.53-0.56), blacks (OR 0.67; 95% CI 0.66-0.68), Hispanics (OR 0.62; 95% CI 0.61-0.63), and Native Americans (OR 0.62; 95% CI 0.58-0.66). CONCLUSION: Females had lower odds of using AV access than do males for hemodialysis initiation. As compared to whites, blacks and Asians were more likely, and Hispanics were less likely to use AV access for first outpatient hemodialysis. Further investigation of biological and process of care factors may help in developing ways to reduce these disparities.
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Arteriovenous Shunt, Surgical / Renal Dialysis / Healthcare Disparities / Central Venous Catheters / Kidney Failure, Chronic Type of study: Observational_studies / Prognostic_studies / Risk_factors_studies Limits: Adolescent / Adult / Aged / Female / Humans / Male / Middle aged Country/Region as subject: America do norte Language: En Journal: Am J Nephrol Year: 2018 Type: Article Affiliation country: United States

Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Arteriovenous Shunt, Surgical / Renal Dialysis / Healthcare Disparities / Central Venous Catheters / Kidney Failure, Chronic Type of study: Observational_studies / Prognostic_studies / Risk_factors_studies Limits: Adolescent / Adult / Aged / Female / Humans / Male / Middle aged Country/Region as subject: America do norte Language: En Journal: Am J Nephrol Year: 2018 Type: Article Affiliation country: United States