Higher parity and risk of metabolic syndrome in Korean postmenopausal women: Korea National Health and Nutrition Examination Survey 2010-2012.
J Obstet Gynaecol Res
; 44(11): 2045-2052, 2018 Nov.
Article
in En
| MEDLINE
| ID: mdl-30058110
ABSTRACT
AIM:
We sought to examine whether parity is associated with higher incidence of metabolic syndrome in postmenopausal women.METHODS:
We conducted a cross-sectional study on 4098 Korean postmenopausal women by using nationally representative data from the Korea National Health and Nutrition Examination Survey 2010-2012. Multivariate logistic regression was performed to evaluate the relationship between parity and metabolic syndrome, with adjustment for potential confounding variables.RESULTS:
The rate of metabolic syndrome was significantly higher with increasing number of parity, with dose-response relationship in univariate analysis (P <0.001). In addition, higher parity (≥3 live births) was associated with more prevalence of all components of metabolic syndrome compared with two live births (parity 2 vs 3 vs ≥4 5.5 vs 12.1 and 14.4%, respectively; P < 0.001). However, after adjusting for demographic, socioeconomic, lifestyle and reproductive factors, we found that only higher parity was significantly associated with metabolic syndrome compared with two live births, and failed to show a dose-dependent relationship (parity 2 vs 3 vs ≥4 odds ratio 1 vs 1.404 vs 1.379, respectively; P = 0.043). We also proved that among the components of metabolic syndrome, only waist circumference had a significant positive relationship with parity in a multivariable adjusted model (parity 2 vs 3 vs ≥4 odds ratio 1 vs 1.559 vs 1.656, respectively; P < 0.001).CONCLUSION:
Higher parity was independently associated with a higher risk of metabolic syndrome in postmenopausal women.Key words
Full text:
1
Collection:
01-internacional
Database:
MEDLINE
Main subject:
Parity
/
Postmenopause
/
Metabolic Syndrome
Type of study:
Etiology_studies
/
Incidence_studies
/
Observational_studies
/
Prevalence_studies
/
Prognostic_studies
/
Risk_factors_studies
Limits:
Aged
/
Female
/
Humans
/
Middle aged
Country/Region as subject:
Asia
Language:
En
Journal:
J Obstet Gynaecol Res
Journal subject:
GINECOLOGIA
/
OBSTETRICIA
Year:
2018
Type:
Article
Affiliation country:
South Korea