A synthetic microRNA-92a inhibitor (MRG-110) accelerates angiogenesis and wound healing in diabetic and nondiabetic wounds.

Gallant-Behm, Corrie L; Piper, Joseph; Dickinson, Brent A; Dalby, Christina M; Pestano, Linda A; Jackson, Aimee L

Gallant-Behm, Corrie L; Piper, Joseph; Dickinson, Brent A; Dalby, Christina M; Pestano, Linda A; Jackson, Aimee L.

Affiliation

Gallant-Behm CL; miRagen Therapeutics, Inc., Boulder, Colorado.
Piper J; miRagen Therapeutics, Inc., Boulder, Colorado.
Dickinson BA; miRagen Therapeutics, Inc., Boulder, Colorado.
Dalby CM; miRagen Therapeutics, Inc., Boulder, Colorado.
Pestano LA; miRagen Therapeutics, Inc., Boulder, Colorado.
Jackson AL; miRagen Therapeutics, Inc., Boulder, Colorado.

Wound Repair Regen ; 26(4): 311-323, 2018 07.

Article in En | MEDLINE | ID: mdl-30118158

Subject(s)

Angiogenesis Inducing Agents/pharmacology; Diabetic Foot/complications; MicroRNAs/antagonists & inhibitors; Wound Healing/drug effects; Wounds and Injuries/complications; Wounds and Injuries/drug therapy; Animals; Endothelial Cells/metabolism; Female; Fibroblasts/metabolism; Gene Expression Regulation/drug effects; Granulation Tissue/pathology; Humans; Male; Mice; Models, Animal; Neovascularization, Pathologic/pathology; Oligonucleotides, Antisense/metabolism; Signal Transduction; Swine

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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Wound Healing / Wounds and Injuries / Diabetic Foot / MicroRNAs / Angiogenesis Inducing Agents Type of study: Prognostic_studies Limits: Animals / Female / Humans / Male Language: En Journal: Wound Repair Regen Journal subject: DERMATOLOGIA Year: 2018 Type: Article

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