Therapeutic potential of artesunate in experimental autoimmune myasthenia gravis by upregulated T regulatory cells and regulation of Th1/Th2 cytokines.

Meng, Qing-Fang; Zhang, Xin-Xin; Zhang, Zheng; Chen, Wei; Li, Xiao-Li; Wang, Yan-Jun; Li, Fei-Fei; Li, Yan-Bin

Meng, Qing-Fang; Zhang, Xin-Xin; Zhang, Zheng; Chen, Wei; Li, Xiao-Li; Wang, Yan-Jun; Li, Fei-Fei; Li, Yan-Bin.

Pharmazie ; 73(9): 526-532, 2018 09 01.

Article in En | MEDLINE | ID: mdl-30223936

Subject(s)

Artesunate/pharmacology; Immunologic Factors/pharmacology; Myasthenia Gravis, Autoimmune, Experimental/drug therapy; T-Lymphocytes, Regulatory/immunology; Animals; Antimalarials/administration & dosage; Antimalarials/pharmacology; Artesunate/administration & dosage; Cell Proliferation/drug effects; Cytokines/immunology; Dose-Response Relationship, Drug; Female; Immunologic Factors/administration & dosage; Myasthenia Gravis, Autoimmune, Experimental/immunology; Myasthenia Gravis, Autoimmune, Experimental/physiopathology; Rats; Rats, Inbred Lew; Th1 Cells/immunology; Th2 Cells/immunology; Up-Regulation

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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: T-Lymphocytes, Regulatory / Myasthenia Gravis, Autoimmune, Experimental / Artesunate / Immunologic Factors Limits: Animals Language: En Journal: Pharmazie Journal subject: FARMACIA Year: 2018 Type: Article

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