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Inhibition of MYC attenuates tumor cell self-renewal and promotes senescence in SMARCB1-deficient Group 2 atypical teratoid rhabdoid tumors to suppress tumor growth in vivo.
Alimova, Irina; Pierce, Angela; Danis, Etienne; Donson, Andrew; Birks, Diane K; Griesinger, Andrea; Foreman, Nicholas K; Santi, Mariarita; Soucek, Laura; Venkataraman, Sujatha; Vibhakar, Rajeev.
Affiliation
  • Alimova I; Department of Pediatrics, University of Colorado Anschutz Medical Campus, Aurora, CO, 80045, USA.
  • Pierce A; Department of Pediatrics, University of Colorado Anschutz Medical Campus, Aurora, CO, 80045, USA.
  • Danis E; Department of Pediatrics, University of Colorado Anschutz Medical Campus, Aurora, CO, 80045, USA.
  • Donson A; Department of Pediatrics, University of Colorado Anschutz Medical Campus, Aurora, CO, 80045, USA.
  • Birks DK; Department of Neurosurgery, University of Colorado Denver, Aurora, CO, 80045, USA.
  • Griesinger A; Department of Pediatrics, University of Colorado Anschutz Medical Campus, Aurora, CO, 80045, USA.
  • Foreman NK; Department of Pediatrics, University of Colorado Anschutz Medical Campus, Aurora, CO, 80045, USA.
  • Santi M; Morgan Adams Foundation Pediatric Brain Tumor Research Program, Children's Hospital Colorado, Aurora, CO, 80045, USA.
  • Soucek L; Department of Neurosurgery, University of Colorado Denver, Aurora, CO, 80045, USA.
  • Venkataraman S; The Children's Hospital of Philadelphia and University of Pennsylvania Perelman, School of Medicine, Philadelphia, PA, 19104, USA.
  • Vibhakar R; Vall d'Hebron Institute of Oncology (VHIO), Cellex Centre, Barcelona, 08035, Spain.
Int J Cancer ; 144(8): 1983-1995, 2019 04 15.
Article in En | MEDLINE | ID: mdl-30230537
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Teratoma / Gene Expression Regulation, Neoplastic / Cell Transformation, Neoplastic / Proto-Oncogene Proteins c-myc / Rhabdoid Tumor / SMARCB1 Protein Type of study: Prognostic_studies Limits: Animals / Female / Humans Language: En Journal: Int J Cancer Year: 2019 Type: Article Affiliation country: United States
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Teratoma / Gene Expression Regulation, Neoplastic / Cell Transformation, Neoplastic / Proto-Oncogene Proteins c-myc / Rhabdoid Tumor / SMARCB1 Protein Type of study: Prognostic_studies Limits: Animals / Female / Humans Language: En Journal: Int J Cancer Year: 2019 Type: Article Affiliation country: United States