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Indirect activation of rhesus macaque (Macaca mulatta) NK cells in oral and mucosal draining lymph nodes.
Ram, Daniel R; Kroll, Kyle; Reeves, R Keith.
Affiliation
  • Ram DR; Harvard Medical School, Center for Virology and Vaccine Research, Beth Israel Deaconess Medical Center, Boston, Massachusetts.
  • Kroll K; Harvard Medical School, Center for Virology and Vaccine Research, Beth Israel Deaconess Medical Center, Boston, Massachusetts.
  • Reeves RK; Harvard Medical School, Center for Virology and Vaccine Research, Beth Israel Deaconess Medical Center, Boston, Massachusetts.
J Med Primatol ; 47(5): 302-304, 2018 10.
Article in En | MEDLINE | ID: mdl-30256418
ABSTRACT
The oral mucosae and draining lymph nodes are primary entry points for invading pathogens, particularly during immunosuppressive HIV/SIV infections. Innate immunity against oral stimuli, including natural killer (NK) cells, is understudied. Herein, we demonstrate functional NK cell responses to pathogen-associated molecular patterns (PAMPs) of potential oral pathogens in rhesus macaques.
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Killer Cells, Natural / Simian Acquired Immunodeficiency Syndrome / Pathogen-Associated Molecular Pattern Molecules / Immunity, Innate / Lymph Nodes / Macaca mulatta Limits: Animals Language: En Journal: J Med Primatol Year: 2018 Type: Article
Fulltext
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PubMed Links
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Killer Cells, Natural / Simian Acquired Immunodeficiency Syndrome / Pathogen-Associated Molecular Pattern Molecules / Immunity, Innate / Lymph Nodes / Macaca mulatta Limits: Animals Language: En Journal: J Med Primatol Year: 2018 Type: Article