Quantitative and synthetic biology approaches to combat bacterial pathogens.
Curr Opin Biomed Eng
; 4: 116-126, 2017 Dec.
Article
in En
| MEDLINE
| ID: mdl-30263975
ABSTRACT
Antibiotic resistance is one of the biggest threats to public health. The rapid emergence of resistant bacterial pathogens endangers the efficacy of current antibiotics and has led to increasing mortality and economic burden. This crisis calls for more rapid and accurate diagnosis to detect and identify pathogens, as well as to characterize their response to antibiotics. Building on this foundation, treatment options also need to be improved to use current antibiotics more effectively and develop alternative strategies that complement the use of antibiotics. We here review recent developments in diagnosis and treatment of bacterial pathogens with a focus on quantitative biology and synthetic biology approaches.
Full text:
1
Collection:
01-internacional
Database:
MEDLINE
Language:
En
Journal:
Curr Opin Biomed Eng
Year:
2017
Type:
Article
Affiliation country:
United States