A guanine-flipping and sequestration mechanism for G-quadruplex unwinding by RecQ helicases.

Voter, Andrew F; Qiu, Yupeng; Tippana, Ramreddy; Myong, Sua; Keck, James L

Voter, Andrew F; Qiu, Yupeng; Tippana, Ramreddy; Myong, Sua; Keck, James L.

Affiliation

Voter AF; Department of Biomolecular Chemistry, University of Wisconsin School of Medicine and Public Health, Madison, WI, 53706, USA.
Qiu Y; Department of Biophysics, Johns Hopkins University, Baltimore, MD, 21218, USA.
Tippana R; Department of Biophysics, Johns Hopkins University, Baltimore, MD, 21218, USA.
Myong S; Department of Biophysics, Johns Hopkins University, Baltimore, MD, 21218, USA.
Keck JL; Department of Biomolecular Chemistry, University of Wisconsin School of Medicine and Public Health, Madison, WI, 53706, USA. jlkeck@wisc.edu.

Nat Commun ; 9(1): 4201, 2018 10 10.

Article in En | MEDLINE | ID: mdl-30305632

Subject(s)

G-Quadruplexes; Guanine/metabolism; RecQ Helicases/metabolism; Binding Sites; Cronobacter sakazakii/enzymology; Guanine/chemistry; Models, Biological; Nucleic Acid Heteroduplexes; Protein Binding; RecQ Helicases/chemistry; Substrate Specificity

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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: RecQ Helicases / G-Quadruplexes / Guanine Language: En Journal: Nat Commun Journal subject: BIOLOGIA / CIENCIA Year: 2018 Type: Article Affiliation country: United States

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