Monensin induces cell death by autophagy and inhibits matrix metalloproteinase 7 (MMP7) in UOK146 renal cell carcinoma cell line.

Verma, Shiv Prakash; Das, Parimal

Verma, Shiv Prakash; Das, Parimal.

Affiliation

Verma SP; Centre for Genetic Disorders, Institute of Science, Banaras Hindu University, Varanasi, 221005, India.
Das P; Centre for Genetic Disorders, Institute of Science, Banaras Hindu University, Varanasi, 221005, India. parimal@bhu.ac.in.

In Vitro Cell Dev Biol Anim ; 54(10): 736-742, 2018 Dec.

Article in En | MEDLINE | ID: mdl-30324243

Subject(s)

Autophagy/drug effects; Carcinoma, Renal Cell/enzymology; Carcinoma, Renal Cell/pathology; Kidney Neoplasms/enzymology; Kidney Neoplasms/pathology; Matrix Metalloproteinase 7/metabolism; Monensin/pharmacology; Autophagy/genetics; Carcinoma, Renal Cell/genetics; Cell Line, Tumor; Cell Movement/drug effects; Cell Proliferation/drug effects; Down-Regulation/drug effects; Gene Expression Regulation, Neoplastic/drug effects; Humans; Kidney Neoplasms/genetics; Matrix Metalloproteinase 7/genetics; Membrane Potential, Mitochondrial/drug effects; RNA, Messenger/genetics; RNA, Messenger/metabolism

Key words

Autophagy; MMP7; Monensin; RCC; UOK 146

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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Autophagy / Monensin / Carcinoma, Renal Cell / Matrix Metalloproteinase 7 / Kidney Neoplasms Limits: Humans Language: En Journal: In Vitro Cell Dev Biol Anim Journal subject: BIOLOGIA Year: 2018 Type: Article Affiliation country: India

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