TWE-PRIL reverse signalling suppresses sympathetic axon growth and tissue innervation.

Howard, Laura; Wosnitzka, Erin; Okakpu, Darian; White, Matthew A; Wyatt, Sean; Davies, Alun M

Howard, Laura; Wosnitzka, Erin; Okakpu, Darian; White, Matthew A; Wyatt, Sean; Davies, Alun M.

Affiliation

Howard L; School of Biosciences, Cardiff University, Museum Avenue, Cardiff, CF10 3AT, UK.
Wosnitzka E; School of Biosciences, Cardiff University, Museum Avenue, Cardiff, CF10 3AT, UK.
Okakpu D; School of Biosciences, Cardiff University, Museum Avenue, Cardiff, CF10 3AT, UK.
White MA; School of Biosciences, Cardiff University, Museum Avenue, Cardiff, CF10 3AT, UK.
Wyatt S; School of Biosciences, Cardiff University, Museum Avenue, Cardiff, CF10 3AT, UK.
Davies AM; School of Biosciences, Cardiff University, Museum Avenue, Cardiff, CF10 3AT, UK daviesalun@cf.ac.uk.

Development ; 145(22)2018 11 19.

Article in En | MEDLINE | ID: mdl-30337376

Subject(s)

Axons/metabolism; Signal Transduction; Tumor Necrosis Factor Ligand Superfamily Member 13/metabolism; Animals; B-Cell Maturation Antigen/genetics; B-Cell Maturation Antigen/metabolism; Cells, Cultured; Cytokine TWEAK/genetics; Cytokine TWEAK/metabolism; Enzyme Activation/drug effects; Extracellular Signal-Regulated MAP Kinases/metabolism; Gene Knockdown Techniques; Mice; Models, Biological; Nerve Growth Factor/pharmacology; Phenotype; RNA, Small Interfering/metabolism; Solubility; Superior Cervical Ganglion/metabolism; Sympathetic Nervous System/growth & development; Tumor Necrosis Factor Ligand Superfamily Member 13/genetics

Key words

Reverse signalling; Sympathetic axons; TNF superfamily; TNFSF13; TNFSFM13; Tissue innervation

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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Axons / Signal Transduction / Tumor Necrosis Factor Ligand Superfamily Member 13 Type of study: Prognostic_studies Limits: Animals Language: En Journal: Development Journal subject: BIOLOGIA / EMBRIOLOGIA Year: 2018 Type: Article Affiliation country: United kingdom

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