Single-molecule nascent RNA sequencing identifies regulatory domain architecture at promoters and enhancers.

Tome, Jacob M; Tippens, Nathaniel D; Lis, John T

Tome, Jacob M; Tippens, Nathaniel D; Lis, John T.

Affiliation

Tome JM; Department of Molecular Biology and Genetics, Cornell University, Ithaca, NY, USA.
Tippens ND; Department of Genome Sciences, University of Washington, Seattle, WA, USA.
Lis JT; Department of Molecular Biology and Genetics, Cornell University, Ithaca, NY, USA.

Nat Genet ; 50(11): 1533-1541, 2018 11.

Article in En | MEDLINE | ID: mdl-30349116

Subject(s)

Enhancer Elements, Genetic; Promoter Regions, Genetic; RNA/analysis; Sequence Analysis, RNA/methods; Transcription Elongation, Genetic; Transcription, Genetic; Base Sequence; Humans; K562 Cells; Protein Binding; RNA/metabolism; RNA Caps/metabolism; RNA Polymerase II/metabolism; Transcription Elongation, Genetic/physiology; Transcription Initiation Site

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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Transcription, Genetic / RNA / Enhancer Elements, Genetic / Promoter Regions, Genetic / Sequence Analysis, RNA / Transcription Elongation, Genetic Type of study: Prognostic_studies Limits: Humans Language: En Journal: Nat Genet Journal subject: GENETICA MEDICA Year: 2018 Type: Article Affiliation country: United States

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