Neurodevelopmental outcomes among extremely premature infants with linear growth restriction.
J Perinatol
; 39(2): 193-202, 2019 02.
Article
in En
| MEDLINE
| ID: mdl-30353080
ABSTRACT
OBJECTIVE:
To compare neurodevelopmental outcomes in linear growth-restricted (LGR) infants born <29 weeks with and without weight gain out of proportion to linear growth. STUDYDESIGN:
We compared 2-year neurodevelopmental outcomes between infants with and without LGR and between LGR infants with and without weight gain out of proportion to linear growth. The outcomes were Bayley-III cognitive, motor, and language scores, cerebral palsy, Gross Motor Function Classification System (GMFCS) level ≥ 2, and neurodevelopmental impairment.RESULT:
In total, 1227 infants were analyzed. LGR infants were smaller and less mature at birth, had higher BMI, and had lower Bayley-III language scores (82.3 vs. 85.0, p < 0.05). Among infants with LGR, infants with high BMI had lower language scores compared with those with low-to-normal BMI (80.8 vs. 83.3, p < 0.05), and were more likely to have GMFCS level ≥2 and neurodevelopmental impairment.CONCLUSION:
Among infants with LGR, weight gain out of proportion to linear growth was associated with poorer neurodevelopmental outcomes.
Full text:
1
Collection:
01-internacional
Database:
MEDLINE
Main subject:
Weight Gain
/
Infant, Extremely Premature
/
Neuropsychological Tests
Type of study:
Diagnostic_studies
/
Observational_studies
/
Risk_factors_studies
Limits:
Female
/
Humans
/
Infant
/
Male
/
Newborn
Country/Region as subject:
America do norte
Language:
En
Journal:
J Perinatol
Journal subject:
PERINATOLOGIA
Year:
2019
Type:
Article
Affiliation country:
United States