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FAM210B is an erythropoietin target and regulates erythroid heme synthesis by controlling mitochondrial iron import and ferrochelatase activity.
Yien, Yvette Y; Shi, Jiahai; Chen, Caiyong; Cheung, Jesmine T M; Grillo, Anthony S; Shrestha, Rishna; Li, Liangtao; Zhang, Xuedi; Kafina, Martin D; Kingsley, Paul D; King, Matthew J; Ablain, Julien; Li, Hojun; Zon, Leonard I; Palis, James; Burke, Martin D; Bauer, Daniel E; Orkin, Stuart H; Koehler, Carla M; Phillips, John D; Kaplan, Jerry; Ward, Diane M; Lodish, Harvey F; Paw, Barry H.
Affiliation
  • Yien YY; From the Department of Biological Sciences, University of Delaware, Newark, Delaware 19716, yyien@udel.edu.
  • Shi J; the Division of Hematology, Brigham and Women's Hospital, Harvard Medical School, Boston, Massachusetts 02115.
  • Chen C; the Whitehead Institute and Department of Biology, Massachusetts Institute of Technology, Cambridge, Massachusetts 02139.
  • Cheung JTM; the Division of Hematology, Brigham and Women's Hospital, Harvard Medical School, Boston, Massachusetts 02115.
  • Grillo AS; the Department of Chemistry and Biochemistry, UCLA, Los Angeles, California 90095.
  • Shrestha R; the Department of Chemistry and Biochemistry, University of Illinois at Urbana-Champaign, Urbana, Illinois 61801.
  • Li L; the Department of Pathology, University of Utah School of Medicine, Salt Lake City, Utah 84112.
  • Zhang X; the Department of Pathology, University of Utah School of Medicine, Salt Lake City, Utah 84112.
  • Kafina MD; From the Department of Biological Sciences, University of Delaware, Newark, Delaware 19716.
  • Kingsley PD; the Division of Hematology, Brigham and Women's Hospital, Harvard Medical School, Boston, Massachusetts 02115.
  • King MJ; the Center for Pediatric Biomedical Research, Department of Pediatrics, University of Rochester Medical Center, Rochester, New York 14642.
  • Ablain J; the Division of Hematology, Brigham and Women's Hospital, Harvard Medical School, Boston, Massachusetts 02115.
  • Li H; the Division of Hematology-Oncology, Boston Children's Hospital, Harvard Medical School, Boston, Massachusetts 02115.
  • Zon LI; the Whitehead Institute and Department of Biology, Massachusetts Institute of Technology, Cambridge, Massachusetts 02139.
  • Palis J; the Division of Hematology-Oncology, Boston Children's Hospital, Harvard Medical School, Boston, Massachusetts 02115.
  • Burke MD; the Department of Pediatric Oncology, Dana-Farber Cancer Institute, Harvard Medical School, Boston, Massachusetts 02115, and.
  • Bauer DE; the Center for Pediatric Biomedical Research, Department of Pediatrics, University of Rochester Medical Center, Rochester, New York 14642.
  • Orkin SH; the Department of Chemistry and Biochemistry, University of Illinois at Urbana-Champaign, Urbana, Illinois 61801.
  • Koehler CM; the Division of Hematology-Oncology, Boston Children's Hospital, Harvard Medical School, Boston, Massachusetts 02115.
  • Phillips JD; the Department of Pediatric Oncology, Dana-Farber Cancer Institute, Harvard Medical School, Boston, Massachusetts 02115, and.
  • Kaplan J; the Division of Hematology-Oncology, Boston Children's Hospital, Harvard Medical School, Boston, Massachusetts 02115.
  • Ward DM; the Department of Pediatric Oncology, Dana-Farber Cancer Institute, Harvard Medical School, Boston, Massachusetts 02115, and.
  • Lodish HF; the Department of Chemistry and Biochemistry, UCLA, Los Angeles, California 90095.
  • Paw BH; the Division of Hematology and Hematologic Malignancy, University of Utah School of Medicine, Salt Lake City, Utah 84112.
J Biol Chem ; 293(51): 19797-19811, 2018 12 21.
Article in En | MEDLINE | ID: mdl-30366982
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Erythropoietin / Mitochondrial Proteins / Erythroid Cells / Ferrochelatase / Heme / Iron / Membrane Proteins / Mitochondria Limits: Animals / Humans Language: En Journal: J Biol Chem Year: 2018 Type: Article
Fulltext
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PubMed Links
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Erythropoietin / Mitochondrial Proteins / Erythroid Cells / Ferrochelatase / Heme / Iron / Membrane Proteins / Mitochondria Limits: Animals / Humans Language: En Journal: J Biol Chem Year: 2018 Type: Article