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Repeated rectal application of a hyperosmolar lubricant is associated with microbiota shifts but does not affect PrEP drug concentrations: results from a randomized trial in men who have sex with men.
Haaland, Richard E; Fountain, Jeffrey; Hu, Yingtian; Holder, Angela; Dinh, Chuong; Hall, LaShonda; Pescatore, Nicole A; Heeke, Sheila; Hart, Clyde E; Xu, Jiahui; Hu, Yi-Juan; Kelley, Colleen F.
Affiliation
  • Haaland RE; Division of HIV/AIDS Prevention, Centers for Disease Control and Prevention, Atlanta, GA, USA.
  • Fountain J; Division of HIV/AIDS Prevention, Centers for Disease Control and Prevention, Atlanta, GA, USA.
  • Hu Y; Department of Biostatistics and Bioinformatics, Rollins School of Public Health, Emory University, Atlanta, GA, USA.
  • Holder A; Division of HIV/AIDS Prevention, Centers for Disease Control and Prevention, Atlanta, GA, USA.
  • Dinh C; Division of HIV/AIDS Prevention, Centers for Disease Control and Prevention, Atlanta, GA, USA.
  • Hall L; Division of Infectious Diseases, Department of Medicine, The Hope Clinic of the Emory Vaccine Center, Emory University School of Medicine, Atlanta, GA, USA.
  • Pescatore NA; Division of Infectious Diseases, Department of Medicine, The Hope Clinic of the Emory Vaccine Center, Emory University School of Medicine, Atlanta, GA, USA.
  • Heeke S; Division of Infectious Diseases, Department of Medicine, The Hope Clinic of the Emory Vaccine Center, Emory University School of Medicine, Atlanta, GA, USA.
  • Hart CE; Division of HIV/AIDS Prevention, Centers for Disease Control and Prevention, Atlanta, GA, USA.
  • Xu J; Department of Biostatistics, St. Jude Children's Research Hospital, Memphis, TN, USA.
  • Hu YJ; Department of Biostatistics and Bioinformatics, Rollins School of Public Health, Emory University, Atlanta, GA, USA.
  • Kelley CF; Division of Infectious Diseases, Department of Medicine, The Hope Clinic of the Emory Vaccine Center, Emory University School of Medicine, Atlanta, GA, USA.
J Int AIDS Soc ; 21(10): e25199, 2018 10.
Article in En | MEDLINE | ID: mdl-30378274
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Rectum / HIV Infections / Homosexuality, Male / Anti-HIV Agents / Lubricants / Pre-Exposure Prophylaxis / Gastrointestinal Microbiome Type of study: Clinical_trials / Risk_factors_studies Limits: Adult / Humans / Male / Middle aged Language: En Journal: J Int AIDS Soc Journal subject: SINDROME DA IMUNODEFICIENCIA ADQUIRIDA (AIDS) Year: 2018 Type: Article Affiliation country: United States
Fulltext
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PubMed Links
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Rectum / HIV Infections / Homosexuality, Male / Anti-HIV Agents / Lubricants / Pre-Exposure Prophylaxis / Gastrointestinal Microbiome Type of study: Clinical_trials / Risk_factors_studies Limits: Adult / Humans / Male / Middle aged Language: En Journal: J Int AIDS Soc Journal subject: SINDROME DA IMUNODEFICIENCIA ADQUIRIDA (AIDS) Year: 2018 Type: Article Affiliation country: United States