Lysophosphatidic acid represses autophagy in prostate carcinoma cells.

Genc, Gizem E; Hipolito, Victoria E B; Botelho, Roberto J; Gumuslu, Saadet

Genc, Gizem E; Hipolito, Victoria E B; Botelho, Roberto J; Gumuslu, Saadet.

Affiliation

Genc GE; a Department of Medical Biochemistry, Faculty of Medicine, Akdeniz University, Antalya 07070, Turkey.
Hipolito VEB; b Department of Chemistry and Biology and the Graduate Program in Molecular Science, Ryerson University, Toronto, ON M5B 2K3, Canada.
Botelho RJ; b Department of Chemistry and Biology and the Graduate Program in Molecular Science, Ryerson University, Toronto, ON M5B 2K3, Canada.
Gumuslu S; a Department of Medical Biochemistry, Faculty of Medicine, Akdeniz University, Antalya 07070, Turkey.

Biochem Cell Biol ; 97(4): 387-396, 2019 08.

Article in En | MEDLINE | ID: mdl-30403494

Subject(s)

Antineoplastic Agents/pharmacology; Autophagy/drug effects; Lysophospholipids/pharmacology; Prostatic Neoplasms/drug therapy; Prostatic Neoplasms/pathology; Cell Proliferation/drug effects; Dose-Response Relationship, Drug; Drug Screening Assays, Antitumor; Humans; Male; Mitogen-Activated Protein Kinase 1/metabolism; Mitogen-Activated Protein Kinase 3/metabolism; Phosphorylation/drug effects; Prostatic Neoplasms/metabolism; Structure-Activity Relationship; TOR Serine-Threonine Kinases/metabolism; Tumor Cells, Cultured

Key words

acide lysophosphatidique; autophagie; autophagy; cancer de la prostate; lysophosphatidic acid; prostate cancer

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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Prostatic Neoplasms / Autophagy / Lysophospholipids / Antineoplastic Agents Limits: Humans / Male Language: En Journal: Biochem Cell Biol Journal subject: BIOQUIMICA Year: 2019 Type: Article Affiliation country: Turkey

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