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Discovery of N-substituted 7-azaindoles as Pan-PIM kinases inhibitors - Lead optimization - Part III.
Barberis, Claude; Pribish, James; Tserlin, Elina; Gross, Alexandre; Czekaj, Mark; Barragué, Matthieu; Erdman, Paul; Maniar, Sachin; Jiang, John; Fire, Luke; Patel, Vinod; Hebert, Andrew; Levit, Mikhail; Wang, Anlai; Sun, Frank; Huang, Shih-Min A.
Affiliation
  • Barberis C; IDD Medicinal Chemistry, Sanofi, 153 Second Avenue, Waltham MA 02451, United States. Electronic address: claude.barberis2@sanofi.com.
  • Pribish J; IDD Medicinal Chemistry, Sanofi, 153 Second Avenue, Waltham MA 02451, United States.
  • Tserlin E; IDD Medicinal Chemistry, Sanofi, 153 Second Avenue, Waltham MA 02451, United States.
  • Gross A; IDD Medicinal Chemistry, Sanofi, 153 Second Avenue, Waltham MA 02451, United States.
  • Czekaj M; IDD Medicinal Chemistry, Sanofi, 153 Second Avenue, Waltham MA 02451, United States.
  • Barragué M; IDD Medicinal Chemistry, Sanofi, 153 Second Avenue, Waltham MA 02451, United States.
  • Erdman P; IDD Medicinal Chemistry, Sanofi, 153 Second Avenue, Waltham MA 02451, United States.
  • Maniar S; IDD Medicinal Chemistry, Sanofi, 153 Second Avenue, Waltham MA 02451, United States.
  • Jiang J; IDD Medicinal Chemistry, Sanofi, 153 Second Avenue, Waltham MA 02451, United States.
  • Fire L; IDD Medicinal Chemistry, Sanofi, 153 Second Avenue, Waltham MA 02451, United States.
  • Patel V; IDD Medicinal Chemistry, Sanofi, 153 Second Avenue, Waltham MA 02451, United States.
  • Hebert A; Oncology Biochemistry, Sanofi, 270 Albany Street, Cambridge MA 02139, United States.
  • Levit M; Oncology Biochemistry, Sanofi, 270 Albany Street, Cambridge MA 02139, United States.
  • Wang A; Oncology Biology, Sanofi, 270 Albany Street, Cambridge MA 02139, United States.
  • Sun F; Oncology Pharmacology, Sanofi, 640 Memorial Drive, Cambridge MA 02139, United States.
  • Huang SA; Oncology Biology, Sanofi, 270 Albany Street, Cambridge MA 02139, United States.
Bioorg Med Chem Lett ; 29(3): 491-495, 2019 02 01.
Article in En | MEDLINE | ID: mdl-30553737
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Protein Kinase Inhibitors / Proto-Oncogene Proteins c-pim-1 / Drug Discovery / Indoles / Antineoplastic Agents Limits: Animals / Humans Language: En Journal: Bioorg Med Chem Lett Journal subject: BIOQUIMICA / QUIMICA Year: 2019 Type: Article
Fulltext
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PubMed Links
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Protein Kinase Inhibitors / Proto-Oncogene Proteins c-pim-1 / Drug Discovery / Indoles / Antineoplastic Agents Limits: Animals / Humans Language: En Journal: Bioorg Med Chem Lett Journal subject: BIOQUIMICA / QUIMICA Year: 2019 Type: Article