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Histone H3 binding to the PHD1 domain of histone demethylase KDM5A enables active site remodeling.
Longbotham, James E; Chio, Cynthia M; Dharmarajan, Venkatasubramanian; Trnka, Michael J; Torres, Idelisse Ortiz; Goswami, Devrishi; Ruiz, Karen; Burlingame, Alma L; Griffin, Patrick R; Fujimori, Danica Galonic.
Affiliation
  • Longbotham JE; Department of Cellular and Molecular Pharmacology, University of California, 600 16th Street, Genentech Hall, San Francisco, CA, 94158, USA.
  • Chio CM; Department of Cellular and Molecular Pharmacology, University of California, 600 16th Street, Genentech Hall, San Francisco, CA, 94158, USA.
  • Dharmarajan V; Department of Molecular Medicine, The Scripps Research Institute, Jupiter, FL, 33458, USA.
  • Trnka MJ; Department of Pharmaceutical Chemistry, University of California, 600 16th Street, Genentech Hall, San Francisco, CA, 94158, USA.
  • Torres IO; Chemistry and Chemical Biology Graduate Program, University of California, 600 16th Street, Genentech Hall, San Francisco, CA, 94158, USA.
  • Goswami D; Department of Molecular Medicine, The Scripps Research Institute, Jupiter, FL, 33458, USA.
  • Ruiz K; TETRAD Graduate Program, University of California, 600 16th Street, Genentech Hall, San Francisco, CA, 94158, USA.
  • Burlingame AL; Department of Pharmaceutical Chemistry, University of California, 600 16th Street, Genentech Hall, San Francisco, CA, 94158, USA.
  • Griffin PR; Department of Molecular Medicine, The Scripps Research Institute, Jupiter, FL, 33458, USA.
  • Fujimori DG; Department of Cellular and Molecular Pharmacology, University of California, 600 16th Street, Genentech Hall, San Francisco, CA, 94158, USA. Danica.Fujimori@ucsf.edu.
Nat Commun ; 10(1): 94, 2019 01 09.
Article in En | MEDLINE | ID: mdl-30626866
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Histones / Retinoblastoma-Binding Protein 2 Type of study: Prognostic_studies Limits: Animals Language: En Journal: Nat Commun Journal subject: BIOLOGIA / CIENCIA Year: 2019 Type: Article Affiliation country: United States
Fulltext
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Histones / Retinoblastoma-Binding Protein 2 Type of study: Prognostic_studies Limits: Animals Language: En Journal: Nat Commun Journal subject: BIOLOGIA / CIENCIA Year: 2019 Type: Article Affiliation country: United States