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Chromatin-Based Classification of Genetically Heterogeneous AMLs into Two Distinct Subtypes with Diverse Stemness Phenotypes.
Yi, Guoqiang; Wierenga, Albertus T J; Petraglia, Francesca; Narang, Pankaj; Janssen-Megens, Eva M; Mandoli, Amit; Merkel, Angelika; Berentsen, Kim; Kim, Bowon; Matarese, Filomena; Singh, Abhishek A; Habibi, Ehsan; Prange, Koen H M; Mulder, André B; Jansen, Joop H; Clarke, Laura; Heath, Simon; van der Reijden, Bert A; Flicek, Paul; Yaspo, Marie-Laure; Gut, Ivo; Bock, Christoph; Schuringa, Jan Jacob; Altucci, Lucia; Vellenga, Edo; Stunnenberg, Hendrik G; Martens, Joost H A.
Affiliation
  • Yi G; Department of Molecular Biology, Faculty of Science, Radboud University, 6525 GA Nijmegen, the Netherlands.
  • Wierenga ATJ; Department of Hematology, University Medical Center Groningen, University of Groningen, 9700 RB Groningen, the Netherlands; Department of Laboratory Medicine, University Medical Center Groningen, University of Groningen, 9700 RB Groningen, the Netherlands.
  • Petraglia F; Dipartimento di Biochimica, Biofisica e Patologia generale, Università degli Studi della Campania "Luigi Vanvitelli," Vico L. De Crecchio 7, 80138 Napoli, Italy.
  • Narang P; Department of Molecular Biology, Faculty of Science, Radboud University, 6525 GA Nijmegen, the Netherlands.
  • Janssen-Megens EM; Department of Molecular Biology, Faculty of Science, Radboud University, 6525 GA Nijmegen, the Netherlands.
  • Mandoli A; Department of Molecular Biology, Faculty of Science, Radboud University, 6525 GA Nijmegen, the Netherlands.
  • Merkel A; Centro Nacional de Análisis Genómico (CNAG), Parc Científic de Barcelona, Barcelona, Spain.
  • Berentsen K; Department of Molecular Biology, Faculty of Science, Radboud University, 6525 GA Nijmegen, the Netherlands.
  • Kim B; Department of Molecular Biology, Faculty of Science, Radboud University, 6525 GA Nijmegen, the Netherlands.
  • Matarese F; Department of Molecular Biology, Faculty of Science, Radboud University, 6525 GA Nijmegen, the Netherlands.
  • Singh AA; Department of Molecular Biology, Faculty of Science, Radboud University, 6525 GA Nijmegen, the Netherlands.
  • Habibi E; Department of Molecular Biology, Faculty of Science, Radboud University, 6525 GA Nijmegen, the Netherlands.
  • Prange KHM; Department of Molecular Biology, Faculty of Science, Radboud University, 6525 GA Nijmegen, the Netherlands.
  • Mulder AB; Department of Hematology, University Medical Center Groningen, University of Groningen, 9700 RB Groningen, the Netherlands.
  • Jansen JH; Department of Laboratory Medicine, Laboratory of Hematology, Radboud University, 6525 GA Nijmegen, the Netherlands.
  • Clarke L; European Molecular Biology Laboratory, European Bioinformatics Institute, Wellcome Genome Campus, Hinxton, Cambridge CB10 1SD, UK.
  • Heath S; Centro Nacional de Análisis Genómico (CNAG), Parc Científic de Barcelona, Barcelona, Spain.
  • van der Reijden BA; Department of Laboratory Medicine, Laboratory of Hematology, Radboud University, 6525 GA Nijmegen, the Netherlands.
  • Flicek P; European Molecular Biology Laboratory, European Bioinformatics Institute, Wellcome Genome Campus, Hinxton, Cambridge CB10 1SD, UK.
  • Yaspo ML; Department of Vertebrate Genomics, Max Planck Institute for Molecular Genetics, 14195 Berlin, Germany.
  • Gut I; Centro Nacional de Análisis Genómico (CNAG), Parc Científic de Barcelona, Barcelona, Spain.
  • Bock C; CeMM Research Center for Molecular Medicine of the Austrian Academy of Sciences, Lazarettgasse 14, 1090 Vienna, Austria; Department of Laboratory Medicine, Medical University of Vienna, 1090 Vienna, Austria; Max Planck Institute for Informatics, Saarland Informatics Campus, 66123 Saarbrücken, German
  • Schuringa JJ; Department of Hematology, University Medical Center Groningen, University of Groningen, 9700 RB Groningen, the Netherlands.
  • Altucci L; Dipartimento di Biochimica, Biofisica e Patologia generale, Università degli Studi della Campania "Luigi Vanvitelli," Vico L. De Crecchio 7, 80138 Napoli, Italy.
  • Vellenga E; Department of Hematology, University Medical Center Groningen, University of Groningen, 9700 RB Groningen, the Netherlands.
  • Stunnenberg HG; Department of Molecular Biology, Faculty of Science, Radboud University, 6525 GA Nijmegen, the Netherlands.
  • Martens JHA; Department of Molecular Biology, Faculty of Science, Radboud University, 6525 GA Nijmegen, the Netherlands. Electronic address: j.martens@ncmls.ru.nl.
Cell Rep ; 26(4): 1059-1069.e6, 2019 01 22.
Article in En | MEDLINE | ID: mdl-30673601
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Nuclear Proteins / Chromatin / Leukemia, Myeloid, Acute / Oncogene Proteins, Fusion / Core Binding Factor Alpha 2 Subunit / Mutation Type of study: Prognostic_studies Limits: Humans Language: En Journal: Cell Rep Year: 2019 Type: Article Affiliation country: Netherlands
Fulltext
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Nuclear Proteins / Chromatin / Leukemia, Myeloid, Acute / Oncogene Proteins, Fusion / Core Binding Factor Alpha 2 Subunit / Mutation Type of study: Prognostic_studies Limits: Humans Language: En Journal: Cell Rep Year: 2019 Type: Article Affiliation country: Netherlands