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Integrated analysis of multiple receptor tyrosine kinases identifies Axl as a therapeutic target and mediator of resistance to sorafenib in hepatocellular carcinoma.
Pinato, David J; Brown, Matthew W; Trousil, Sebastian; Aboagye, Eric O; Beaumont, Jamie; Zhang, Hua; Coley, Helen M; Mauri, Francesco A; Sharma, Rohini.
Affiliation
  • Pinato DJ; Department of Surgery and Cancer, Imperial College London, Hammersmith Hospital Campus, Du Cane Road, London, W12 0NN, UK. david.pinato@imperial.ac.uk.
  • Brown MW; Department of Surgery and Cancer, Imperial College London, Hammersmith Hospital Campus, Du Cane Road, London, W12 0NN, UK.
  • Trousil S; Department of Surgery and Cancer, Imperial College London, Hammersmith Hospital Campus, Du Cane Road, London, W12 0NN, UK.
  • Aboagye EO; Department of Surgery and Cancer, Imperial College London, Hammersmith Hospital Campus, Du Cane Road, London, W12 0NN, UK.
  • Beaumont J; Department of Surgery and Cancer, Imperial College London, Hammersmith Hospital Campus, Du Cane Road, London, W12 0NN, UK.
  • Zhang H; Department of Oncology, New York University, Laura and Isaac Perlmutter Cancer Center, New York, NY, USA.
  • Coley HM; Faculty of Health and Medical Sciences, University of Surrey, Guildford, Surrey, UK.
  • Mauri FA; Department of Surgery and Cancer, Imperial College London, Hammersmith Hospital Campus, Du Cane Road, London, W12 0NN, UK.
  • Sharma R; Department of Histopathology, Imperial College London, Hammersmith Hospital Campus, Du Cane Road, London, W12 0HS, UK.
Br J Cancer ; 120(5): 512-521, 2019 03.
Article in En | MEDLINE | ID: mdl-30765873
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Proto-Oncogene Proteins / Receptor Protein-Tyrosine Kinases / Carcinoma, Hepatocellular / Drug Resistance, Neoplasm / Sorafenib / Liver Neoplasms / Antineoplastic Agents Limits: Adult / Aged / Female / Humans / Male / Middle aged Language: En Journal: Br J Cancer Year: 2019 Type: Article Affiliation country: United kingdom
Fulltext
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Proto-Oncogene Proteins / Receptor Protein-Tyrosine Kinases / Carcinoma, Hepatocellular / Drug Resistance, Neoplasm / Sorafenib / Liver Neoplasms / Antineoplastic Agents Limits: Adult / Aged / Female / Humans / Male / Middle aged Language: En Journal: Br J Cancer Year: 2019 Type: Article Affiliation country: United kingdom