Superficial candidosis course in patients with carbohydrate metabolism disorder and diabetes mellitus.
Wiad Lek
; 72(1): 68-71, 2019.
Article
in En
| MEDLINE
| ID: mdl-30796865
ABSTRACT
OBJECTIVE:
Introduction:
One of the pressing issues of modern dermatology is the prevalence of diseases of skin and mucous membranes caused by yeast-like fungi. Theaim:
To study specific features of the course of skin and mucous membranes superficial candidosis against the background of initial carbohydrate metabolism disorders or diabetes mellitus. PATIENTS ANDMETHODS:
Materials andmethods:
We have examined 93 patients aged 18-75 suffering from superficial candidosis. Candidosis was diagnosed based on anamnesis data, results of clinical tests and laboratory studies. The study of carbohydrate metabolism included determining of the glucose level under fasting conditions to establish possible diabetes mellitus and glucose tolerance test (75 g glucose load), glycosylated hemoglobin (HbA1c) and fructosamine (FR).RESULTS:
Results:
In patients with mild and moderate candidosis we have detected an increased rates of ÐbA1Ñ and fructosamine, as compared with the like indicators received in the control group, by 1.54 and 1.21 times respectively. In patients with severe candidosis and relapses the concentrations of ÐbA1Ñ increased by 2.59 times, FR - by 2.26 times against the indicators received in the control group. Thus, increased levels of blood glycosylated protein indicate the pathogenetic importance of these processes in the development of candidosis.CONCLUSION:
Conclusions:
Consequently, increased levels of blood glycosylated protein indicates the pathogenetic importance of these processes in the development of candidal lesions. Tests for ÐbA1Ñ and FR proved to be sensitive and allow reliable detection of individuals with diabetes mellitus and glucose intolerance among candidosis patients.Key words
Search on Google
Collection:
01-internacional
Database:
MEDLINE
Main subject:
Candidiasis
/
Carbohydrate Metabolism, Inborn Errors
/
Diabetes Mellitus
Type of study:
Risk_factors_studies
Limits:
Adolescent
/
Adult
/
Aged
/
Humans
/
Middle aged
Language:
En
Journal:
Wiad Lek
Journal subject:
MEDICINA
Year:
2019
Type:
Article
Affiliation country:
Ukraine