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Association of Genetic Variants in NUDT15 With Thiopurine-Induced Myelosuppression in Patients With Inflammatory Bowel Disease.
Walker, Gareth J; Harrison, James W; Heap, Graham A; Voskuil, Michiel D; Andersen, Vibeke; Anderson, Carl A; Ananthakrishnan, Ashwin N; Barrett, Jeffrey C; Beaugerie, Laurent; Bewshea, Claire M; Cole, Andy T; Cummings, Fraser R; Daly, Mark J; Ellul, Pierre; Fedorak, Richard N; Festen, Eleonora A M; Florin, Timothy H; Gaya, Daniel R; Halfvarson, Jonas; Hart, Ailsa L; Heerasing, Neel M; Hendy, Peter; Irving, Peter M; Jones, Samuel E; Koskela, Jukka; Lindsay, James O; Mansfield, John C; McGovern, Dermot; Parkes, Miles; Pollok, Richard C G; Ramakrishnan, Subramaniam; Rampton, David S; Rivas, Manuel A; Russell, Richard K; Schultz, Michael; Sebastian, Shaji; Seksik, Philippe; Singh, Abhey; So, Kenji; Sokol, Harry; Subramaniam, Kavitha; Todd, Anthony; Annese, Vito; Weersma, Rinse K; Xavier, Ramnik; Ward, Rebecca; Weedon, Michael N; Goodhand, James R; Kennedy, Nicholas A; Ahmad, Tariq.
Affiliation
  • Walker GJ; Department of Gastroenterology, Royal Devon and Exeter Hospital NHS Foundation Trust, Exeter, England.
  • Harrison JW; IBD Pharmacogenetics Group, University of Exeter, Exeter, England.
  • Heap GA; University of Exeter Medical School, Exeter, England.
  • Voskuil MD; Department of Gastroenterology, Royal Devon and Exeter Hospital NHS Foundation Trust, Exeter, England.
  • Andersen V; IBD Pharmacogenetics Group, University of Exeter, Exeter, England.
  • Anderson CA; Department of Gastroenterology and Hepatology, University Medical Center Groningen, Groningen, the Netherlands.
  • Ananthakrishnan AN; Medical Department, Regional Hospital Viborg, Viborg, Denmark.
  • Barrett JC; Wellcome Trust Sanger Institute, Hinxton, England.
  • Beaugerie L; Department of Gastroenterology, Massachusetts General Hospital, Boston.
  • Bewshea CM; Wellcome Trust Sanger Institute, Hinxton, England.
  • Cole AT; Department of Gastroenterology, Saint-Antoine Hospital and Sorbonne Universite, Paris, France.
  • Cummings FR; IBD Pharmacogenetics Group, University of Exeter, Exeter, England.
  • Daly MJ; Derby Digestive Diseases Centre, Royal Derby Hospital, Derby Teaching Hospitals NHS Foundation Trust, Derby, England.
  • Ellul P; Department of Gastroenterology, Southampton General Hospital, University Hospital Southampton NHS Foundation Trust, Southampton, England.
  • Fedorak RN; Broad Institute, Harvard University, Cambridge, Massachusetts.
  • Festen EAM; Department of Gastroenterology, Mater Dei Hospital, Msida, Malta.
  • Florin TH; Division of Gastroenterology, University of Alberta, Edmonton, Canada.
  • Gaya DR; Department of Gastroenterology and Hepatology, University Medical Center Groningen, Groningen, the Netherlands.
  • Halfvarson J; Mater Research Institute, University of Queensland, South Brisbane, Australia.
  • Hart AL; Department of Gastroenterology, Glasgow Royal Infirmary, NHS Greater Glasgow and Clyde, Glasgow, Scotland.
  • Heerasing NM; Division of Gastroenterology, Örebro University, Örebro, Sweden.
  • Hendy P; Department of Gastroenterology, St Mark's Hospital, London North West Healthcare NHS Trust, Harrow, England.
  • Irving PM; Department of Gastroenterology, Royal Devon and Exeter Hospital NHS Foundation Trust, Exeter, England.
  • Jones SE; IBD Pharmacogenetics Group, University of Exeter, Exeter, England.
  • Koskela J; Department of Gastroenterology, Royal Devon and Exeter Hospital NHS Foundation Trust, Exeter, England.
  • Lindsay JO; IBD Pharmacogenetics Group, University of Exeter, Exeter, England.
  • Mansfield JC; Department of Gastroenterology, Guy's and St Thomas' NHS Foundation Trust, London, England.
  • McGovern D; University of Exeter Medical School, Exeter, England.
  • Parkes M; Broad Institute, Harvard University, Cambridge, Massachusetts.
  • Pollok RCG; Centre for Immunobiology, Blizard Institute, Barts and the London School of Medicine, Queen Mary University of London, London, England.
  • Ramakrishnan S; Department of Gastroenterology, Newcastle upon Tyne Hospitals NHS Foundation Trust, Newcastle upon Tyne, England.
  • Rampton DS; F. Widjaja Foundation Inflammatory Bowel Disease and Immunobiology Research Institute, Cedars-Sinai Medical Center, Los Angeles, California.
  • Rivas MA; Department of Gastroenterology, Addenbrooke's Hospital, Cambridge University Hospitals NHS Foundation Trust, Cambridge, England.
  • Russell RK; Department of Gastroenterology, St George's Healthcare NHS Trust, Tooting, England.
  • Schultz M; Gastrointestinal and Liver Services, Warrington and Halton Hospitals NHS Foundation Trust, Warrington, England.
  • Sebastian S; Department of Gastroenterology, Royal London Hospital, Barts Health NHS Trust, London, England.
  • Seksik P; Broad Institute, Harvard University, Cambridge, Massachusetts.
  • Singh A; Department of Paediatric Gastroenterology, Royal Hospital for Children, NHS Greater Glasgow and Clyde, Glasgow, Scotland.
  • So K; Dunedin Hospital, Dunedin, New Zealand.
  • Sokol H; Gastroenterology and Hepatology, Hull and East Yorkshire Hospitals NHS Trust, Hull, England.
  • Subramaniam K; Department of Gastroenterology, Saint-Antoine Hospital and Sorbonne Universite, Paris, France.
  • Todd A; Department of Gastroenterology, Royal Devon and Exeter Hospital NHS Foundation Trust, Exeter, England.
  • Annese V; Department of Gastroenterology, Royal Devon and Exeter Hospital NHS Foundation Trust, Exeter, England.
  • Weersma RK; Department of Gastroenterology, Saint-Antoine Hospital and Sorbonne Universite, Paris, France.
  • Xavier R; Canberra Hospital, Canberra, Australia.
  • Ward R; Department of Haematology, Royal Devon and Exeter Hospital NHS Foundation Trust, Exeter, England.
  • Weedon MN; Division of Gastroenterology, Azienda Ospedaliero Universitaria Careggi, Florence, Italy.
  • Goodhand JR; Department of Gastroenterology and Hepatology, University Medical Center Groningen, Groningen, the Netherlands.
  • Kennedy NA; Broad Institute, Harvard University, Cambridge, Massachusetts.
  • Ahmad T; University of Exeter Medical School, Exeter, England.
JAMA ; 321(8): 773-785, 2019 02 26.
Article in En | MEDLINE | ID: mdl-30806694
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Pyrophosphatases / Colitis, Ulcerative / Crohn Disease / Methyltransferases Type of study: Observational_studies / Prognostic_studies / Risk_factors_studies Limits: Adolescent / Adult / Female / Humans / Male Language: En Journal: JAMA Year: 2019 Type: Article Affiliation country: United kingdom
Fulltext
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Pyrophosphatases / Colitis, Ulcerative / Crohn Disease / Methyltransferases Type of study: Observational_studies / Prognostic_studies / Risk_factors_studies Limits: Adolescent / Adult / Female / Humans / Male Language: En Journal: JAMA Year: 2019 Type: Article Affiliation country: United kingdom