Resolution of (R,S)-ibuprofen catalyzed by immobilized Novozym40086 in organic phase.

Yuan, Xin; Wang, Lujun; Liu, Guangyong; Dai, Guilin; Tang, Kewen

Yuan, Xin; Wang, Lujun; Liu, Guangyong; Dai, Guilin; Tang, Kewen.

Affiliation

Yuan X; Department of Chemistry and Chemical Engineering, Hunan Institute of Science and Technology, Yueyang, China.
Wang L; Department of Chemistry and Chemical Engineering, Hunan Institute of Science and Technology, Yueyang, China.
Liu G; Department of Chemistry and Chemical Engineering, Hunan Institute of Science and Technology, Yueyang, China.
Dai G; Department of Chemistry and Chemical Engineering, Hunan Institute of Science and Technology, Yueyang, China.
Tang K; Department of Chemistry and Chemical Engineering, Hunan Institute of Science and Technology, Yueyang, China.

Chirality ; 31(6): 445-456, 2019 Jun.

Article in En | MEDLINE | ID: mdl-30974019

Subject(s)

Enzymes, Immobilized/metabolism; Ibuprofen/chemistry; Lipase/metabolism; Catalysis; Enzymes, Immobilized/chemistry; Esterification; Hexanols/chemistry; Ibuprofen/analysis; Lipase/chemistry; Models, Chemical; Reproducibility of Results; Solvents/chemistry; Stereoisomerism; Temperature; Thermodynamics

Key words

enantioselectivity; enzymatic kinetic resolution; esterification; ibuprofen; immobilized Novozym40086

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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Ibuprofen / Enzymes, Immobilized / Lipase Type of study: Prognostic_studies Language: En Journal: Chirality Journal subject: BIOLOGIA MOLECULAR / QUIMICA Year: 2019 Type: Article Affiliation country: China

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