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Drug prioritization using the semantic properties of a knowledge graph.
Malas, Tareq B; Vlietstra, Wytze J; Kudrin, Roman; Starikov, Sergey; Charrout, Mohammed; Roos, Marco; Peters, Dorien J M; Kors, Jan A; Vos, Rein; 't Hoen, Peter A C; van Mulligen, Erik M; Hettne, Kristina M.
Affiliation
  • Malas TB; Department of Human Genetics, Leiden University Medical Center, 2300 RC, Leiden, The Netherlands.
  • Vlietstra WJ; Department of Medical Informatics, Erasmus MC, University Medical Center Rotterdam, 3000 CA, Rotterdam, The Netherlands.
  • Kudrin R; Faculty of Bioengineering and Bioinformatics, Moscow State University, 119234, Moscow, Russia.
  • Starikov S; Faculty of Bioengineering and Bioinformatics, Moscow State University, 119234, Moscow, Russia.
  • Charrout M; Department of Human Genetics, Leiden University Medical Center, 2300 RC, Leiden, The Netherlands.
  • Roos M; Department of Human Genetics, Leiden University Medical Center, 2300 RC, Leiden, The Netherlands.
  • Peters DJM; Department of Human Genetics, Leiden University Medical Center, 2300 RC, Leiden, The Netherlands.
  • Kors JA; Department of Medical Informatics, Erasmus MC, University Medical Center Rotterdam, 3000 CA, Rotterdam, The Netherlands.
  • Vos R; Department of Medical Informatics, Erasmus MC, University Medical Center Rotterdam, 3000 CA, Rotterdam, The Netherlands.
  • 't Hoen PAC; Department of Methodology and Statistics, Maastricht University, 6200 MD, Maastricht, The Netherlands.
  • van Mulligen EM; Department of Human Genetics, Leiden University Medical Center, 2300 RC, Leiden, The Netherlands.
  • Hettne KM; Centre for Molecular and Biomolecular Informatics, Radboud Institute for Molecular Life Sciences, Radboud University Medical Center, 6500 HB, Nijmegen, The Netherlands.
Sci Rep ; 9(1): 6281, 2019 04 18.
Article in En | MEDLINE | ID: mdl-31000794
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Semantics / Polycystic Kidney, Autosomal Dominant / Information Dissemination / Drug Repositioning Type of study: Clinical_trials / Prognostic_studies Limits: Humans Language: En Journal: Sci Rep Year: 2019 Type: Article Affiliation country: Netherlands
Fulltext
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Semantics / Polycystic Kidney, Autosomal Dominant / Information Dissemination / Drug Repositioning Type of study: Clinical_trials / Prognostic_studies Limits: Humans Language: En Journal: Sci Rep Year: 2019 Type: Article Affiliation country: Netherlands