Function of the cargo sorting dileucine motif in a cytomegalovirus immune evasion protein.

Fink, Annette; Mikulicic, Snjezana; Blaum, Franziska; Reddehase, Matthias J; Florin, Luise; Lemmermann, Niels A W

Fink, Annette; Mikulicic, Snjezana; Blaum, Franziska; Reddehase, Matthias J; Florin, Luise; Lemmermann, Niels A W.

Affiliation

Fink A; Institute for Virology, University Medical Center of the Johannes Gutenberg-University Mainz and Research Center for Immunotherapy (FZI), Obere Zahlbacher Strasse 67, Hochhaus am Augustusplatz, 55131, Mainz, Germany.
Mikulicic S; Transplantation Immunology, Institute of Immunology, Heidelberg University Hospital, Im Neuenheimer Feld 305, 69120, Heidelberg, Germany.
Blaum F; Institute for Virology, University Medical Center of the Johannes Gutenberg-University Mainz and Research Center for Immunotherapy (FZI), Obere Zahlbacher Strasse 67, Hochhaus am Augustusplatz, 55131, Mainz, Germany.
Reddehase MJ; Institute for Virology, University Medical Center of the Johannes Gutenberg-University Mainz and Research Center for Immunotherapy (FZI), Obere Zahlbacher Strasse 67, Hochhaus am Augustusplatz, 55131, Mainz, Germany.
Florin L; Institute for Virology, University Medical Center of the Johannes Gutenberg-University Mainz and Research Center for Immunotherapy (FZI), Obere Zahlbacher Strasse 67, Hochhaus am Augustusplatz, 55131, Mainz, Germany. matthias.reddehase@uni-mainz.de.
Lemmermann NAW; Institute for Virology, University Medical Center of the Johannes Gutenberg-University Mainz and Research Center for Immunotherapy (FZI), Obere Zahlbacher Strasse 67, Hochhaus am Augustusplatz, 55131, Mainz, Germany. lflorin@uni-mainz.de.

Med Microbiol Immunol ; 208(3-4): 531-542, 2019 Aug.

Article in En | MEDLINE | ID: mdl-31004199

Subject(s)

Cytomegalovirus Infections/immunology; Histocompatibility Antigens Class I/metabolism; Immune Evasion; Muromegalovirus/growth & development; Muromegalovirus/immunology; Viral Proteins/metabolism; Virulence Factors/metabolism; Animals; Cells, Cultured; Endosomes/metabolism; Lysosomes/metabolism; Mice, Inbred BALB C; Mice, Inbred C57BL; Protein Binding; Protein Transport

Key words

Adapter proteins (AP-1, AP-3); Antigen presentation; Cargo sorting; Cytomegalovirus; Dileucine motif; Early endosomes (EE); Endosomal pathway; Endosomal recycling compartment (ERC); Immune evasion; Late endosomes (LE); MHC class-I; MHC class-I trafficking; Trans-Golgi network (TGN); m06 protein

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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Viral Proteins / Histocompatibility Antigens Class I / Muromegalovirus / Cytomegalovirus Infections / Virulence Factors / Immune Evasion Type of study: Prognostic_studies Limits: Animals Language: En Journal: Med Microbiol Immunol Year: 2019 Type: Article Affiliation country: Germany

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